RPE65

Gene Name		retinal pigment epithelium-specific protein 65kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Organelle Membrane Cell Body
	Molecular Function	Retinal Isomerase Activity Metal Ion Binding All-trans-retinyl-palmitate Hydrolase, 11-cis Retinol Forming Activity All-trans-retinyl-ester Hydrolase, 11-cis Retinol Forming Activity
	Biological Process	Retinoid Metabolic Process Retina Homeostasis Vitamin A Metabolic Process Regulation Of Rhodopsin Gene Expression Visual Perception Phototransduction, Visible Light Insulin Receptor Signaling Pathway Retinol Metabolic Process Retinal Metabolic Process Detection Of Light Stimulus Involved In Visual Perception Retina Morphogenesis In Camera-type Eye Cellular Response To Electrical Stimulus
Pathways		Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Diseases associated with visual transduction
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: RBP4 SLC27A1
Entrez ID		6121
HPRD ID		01569
Ensembl ID		ENSG00000116745
Uniprot IDs		Q16518
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Insulin Medium-chain Fatty Acid Transport Lipid Transport Lipid Localization Alcohol Metabolic Process Retinol Transport Female Genitalia Morphogenesis Negative Regulation Of Phospholipid Biosynthetic Process Response To Peptide Hormone Urinary Bladder Development Response To Peptide Phosphatidylserine Biosynthetic Process Cardiolipin Biosynthetic Process Positive Regulation Of Immunoglobulin Secretion Adiponectin-activated Signaling Pathway Positive Regulation Of Heat Generation Cardiolipin Metabolic Process Phosphatidylglycerol Biosynthetic Process Phosphatidylethanolamine Biosynthetic Process Negative Regulation Of Cardiac Muscle Cell Proliferation Embryonic Retina Morphogenesis In Camera-type Eye Regulation Of Immunoglobulin Secretion Detection Of Light Stimulus Involved In Visual Perception Retinal Metabolic Process Response To Organonitrogen Compound Maintenance Of Gastrointestinal Epithelium Vagina Development Heart Trabecula Formation Uterus Development Genitalia Morphogenesis Response To Hormone Epithelial Structure Maintenance Cellular Lipid Metabolic Process Negative Regulation Of Cardiac Muscle Tissue Development Female Genitalia Development Phosphatidylcholine Biosynthetic Process Phosphatidic Acid Biosynthetic Process Retinol Metabolic Process Phosphatidic Acid Metabolic Process Response To Abiotic Stimulus Heart Trabecula Morphogenesis Phosphatidylserine Metabolic Process Lipid Metabolic Process Negative Regulation Of Organ Growth Positive Regulation Of Immunoglobulin Production Long-chain Fatty Acid Transport Negative Regulation Of Lipid Biosynthetic Process Regulation Of Cardiac Muscle Cell Proliferation Vitamin Transport Negative Regulation Of Striated Muscle Tissue Development
Tagcloud ?		acyltransferase amaurosis blindness combinatorial cone culprit cyclase degeneration disrupt emphasizes galphat2 gc1 grk1 guanylate hereditary lca leber lecithin lrat mistrafficking opn1sw opsin opsins photoreceptor photoreceptors retinal retinol transducin vision