RNASE2

Description		ribonuclease A family member 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Lysosome Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Lipopolysaccharide Binding Nucleic Acid Binding Nuclease Activity Endonuclease Activity Ribonuclease A Activity RNA Nuclease Activity Protein Binding Hydrolase Activity Lyase Activity
	Biological Process	Innate Immune Response In Mucosa RNA Catabolic Process Chemotaxis Induction Of Bacterial Agglutination Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Defense Response To Virus
Pathways		Neutrophil degranulation
Drugs		Adenosine 3',5'-diphosphate Adenosine-2'-5'-Diphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 20570966)
Interacting Genes		4 interacting genes: ABCE1 DLG2 GEMIN4 YWHAQ
Entrez ID		6036
HPRD ID		00577
Ensembl ID		ENSG00000169385
Uniprot IDs		P10153 W0UV60
PDB IDs		1GQV 1HI2 1HI3 1HI4 1HI5 1K2A 2BEX 2BZZ 2C01 2C02 2C05 5E13 6SSO 8F5X 8QEW
Enriched GO Terms of Interacting Partners?		Retrograde Axonal Protein Transport Endoribonuclease Inhibitor Activity Regulation Of Endoribonuclease Activity Negative Regulation Of Endoribonuclease Activity Negative Regulation Of Nuclease Activity Regulation Of Ribonuclease Activity Cytoplasmic Translational Elongation CTPase Activity CAT Tailing Juxtaparanode Region Of Axon GMP Kinase Activity GDP Metabolic Process Protein Transport Along Microtubule Anterograde Axonal Protein Transport Ribonucleoside Triphosphate Phosphatase Activity Translational Termination Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Protein Ufmylation SMN Complex Gemini Of Cajal Bodies Cellular Response To Potassium Ion Small Nuclear Ribonucleoprotein Complex SMN-Sm Protein Complex Response To Potassium Ion Retrograde Axonal Transport Ribosomal Small Subunit Binding
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