RFXAP

Description		regulatory factor X associated protein
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GO Annotations	Cellular Component	Nucleus Nuclear Speck RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency Bare lymphocyte syndrome (BLS) type2
GWAS		Metabolite levels ( 23823483) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)
Novel Interacting Genes		3 novel interacting genes: GABBR2 HTR2A TSC22D1
Interacting Genes		4 interacting genes: EPS8 RFX5 RFXANK SMARCA4
Entrez ID		5994
HPRD ID		03515
Ensembl ID		ENSG00000133111
Uniprot IDs		O00287
PDB IDs		2KW3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of MHC Class II Biosynthetic Process Transcription Coregulator Binding
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