RBP4

Name	retinol binding protein 4
Structure
Novel Interactors	1 novel interactors: TLL2
Interactors	7 interactors: ALB GRB2 LAMTOR5 RBBP6 RIPPLY3 RPE65 TTR
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Protein-containing Complex Extracellular Exosome
	Molecular Function	Retinoid Binding Protein Binding Retinal Binding Retinol Binding Retinol Transmembrane Transporter Activity Protein-containing Complex Binding Molecular Carrier Activity
	Biological Process	Retinoid Metabolic Process Eye Development Positive Regulation Of Immunoglobulin Production Gluconeogenesis Spermatogenesis Heart Development Visual Perception Phototransduction, Visible Light Male Gonad Development Response To Xenobiotic Stimulus Response To Muscle Activity Maintenance Of Gastrointestinal Epithelium Lung Development Positive Regulation Of Insulin Secretion Response To Retinoic Acid Response To Insulin Retinol Transport Retinol Metabolic Process Retinal Metabolic Process Glucose Homeostasis Response To Ethanol Embryonic Organ Morphogenesis Embryonic Skeletal System Development Cardiac Muscle Tissue Development Female Genitalia Morphogenesis Detection Of Light Stimulus Involved In Visual Perception Retina Development In Camera-type Eye Negative Regulation Of Cardiac Muscle Cell Proliferation Embryonic Retina Morphogenesis In Camera-type Eye Uterus Development Vagina Development Urinary Bladder Development Heart Trabecula Formation Vitamin A Import Into Cell
Pathways	The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism disease events Retinoid metabolism and transport Defective visual phototransduction due to STRA6 loss of function
Drugs	Tretinoin
GWAS	Blood protein levels ( 30072576 ) Optic disc area ( 31798171 ) Retinol levels ( 21878437 )
Entrez ID	5950
HPRD ID	01580
Ensembl ID	ENSG00000138207
Uniprot IDs	P02753 Q5VY30
PDB IDs	1BRP 1BRQ 1JYD 1JYJ 1QAB 1RBP 1RLB 2WQ9 2WQA 2WR6 3BSZ 3FMZ 4O9S 4PSQ 5NTY 5NU2 5NU6 5NU7 5NU8 5NU9 5NUA 5NUB 6QBA
GO Terms Enriched among Interactors ?	Protein-containing Complex Enterobactin Binding Exogenous Protein Binding Cellular Response To Calcium Ion Starvation Guanyl-nucleotide Exchange Factor Adaptor Activity Response To Radiation Grb2-EGFR Complex Terpenoid Metabolic Process All-trans-retinyl-palmitate Hydrolase, 11-cis Retinol Forming Activity Retinoid Metabolic Process All-trans-retinyl-ester Hydrolase, 11-cis Retinol Forming Activity Zeaxanthin Biosynthetic Process Retinol Isomerase Activity Diterpenoid Metabolic Process Xanthophyll Metabolic Process Detection Of Light Stimulus Negative Regulation Of Skeletal Muscle Tissue Growth Isoprenoid Metabolic Process Carotenoid Metabolic Process Beta-carotene 15,15'-dioxygenase Activity Detection Of Abiotic Stimulus Negative Regulation Of Glomerular Filtration Ragulator Complex Neurotrophin TRKA Receptor Binding Vitamin A Metabolic Process Regulation Of Skeletal Muscle Tissue Growth