TLNRD1

Description		talin rod domain containing 1
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GO Annotations	Cellular Component	Stress Fiber
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 33020668) Myocardial infarction ( 33532862)
Interacting Genes		4 interacting genes: CCM2 LRP6 PICK1 SH2B2
Entrez ID		59274
HPRD ID		11300
Ensembl ID		ENSG00000140406
Uniprot IDs		Q9H1K6
PDB IDs		6XZ3 6XZ4
Enriched GO Terms of Interacting Partners?		Wnt Signalosome Wnt-Frizzled-LRP5/6 Complex Midbrain Dopaminergic Neuron Differentiation Embryo Development Ending In Birth Or Egg Hatching Wnt Receptor Activity Signaling Receptor Binding Multicellular Organism Development Toxin Transmembrane Transporter Activity Kinase Inhibitor Activity Cellular Developmental Process Low-density Lipoprotein Particle Receptor Activity Neural Crest Formation Neural Crest Cell Differentiation Chordate Embryonic Development Cellular Response To Cholesterol Protein Localization To Membrane Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Membrane Curvature Sensor Activity Negative Regulation Of Actin Nucleation Neuronal Ion Channel Clustering Arp2/3 Complex Binding Dendritic Spine Maintenance Long-term Synaptic Depression Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity B-1 B Cell Homeostasis Venous Blood Vessel Morphogenesis Endothelial Tube Morphogenesis Pericardium Development Blood Vessel Endothelial Cell Differentiation Endothelium Development Negative Regulation Of Smooth Muscle Cell Apoptotic Process Cellular Response To Sterol Response To Cholesterol Cell Surface Receptor Signaling Pathway Localization Within Membrane Protein Serine/threonine Kinase Inhibitor Activity Wnt-protein Binding Positive Regulation Of Receptor Internalization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Monoamine Transport Brown Fat Cell Differentiation B Cell Homeostasis Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Endothelial Cell Differentiation
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