RAD17

Gene Name		RAD17 homolog (S. pombe)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm
	Molecular Function	Protein Binding ATP Binding
	Biological Process	DNA Replication Checkpoint DNA Damage Checkpoint DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Negative Regulation Of DNA Replication Regulation Of Phosphorylation
Pathways		G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Protein-protein Interactions		16 interactors: ATM ATR HUS1 MCM7 NHP2L1 POLE PRKDC PRMT6 RAD1 RAD9A RAD9B RFC2 RFC3 RFC4 RFC5 USP20
Entrez ID		5884
HPRD ID		09124
Ensembl ID		ENSG00000152942
Uniprot IDs		O75943
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus DNA Repair DNA Replication DNA Metabolic Process Cell Cycle Process Cellular Response To Stress DNA Recombination Telomere Maintenance Cell Cycle Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication DNA Damage Checkpoint Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Cell Cycle Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Transcription-coupled Nucleotide-excision Repair Cell Cycle Checkpoint DNA-dependent DNA Replication Response To Stress Response To Ionizing Radiation Nucleobase-containing Compound Metabolic Process Cellular Response To Ionizing Radiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleotide-excision Repair Chromosome Organization Nitrogen Compound Metabolic Process Cellular Response To Radiation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Response To Radiation Biosynthetic Process Cellular Response To Stimulus Cellular Metabolic Process Double-strand Break Repair Mitotic Cell Cycle Process Mitotic Cell Cycle Checkpoint Response To Gamma Radiation Organelle Organization Negative Regulation Of Cell Cycle Positive Regulation Of Response To DNA Damage Stimulus Negative Regulation Of Mitotic Cell Cycle Homeostatic Process
Tagcloud ?		acetylcysteine antioxidant chk1 converted depleted driving experiencing gamma h2ax h2o2 illustrate instability intertwined micronuclei mildly mimics mn nac p400 pan peroxide promoting redox reinforce rnai ros sesn1 stressed subclass