ARHGAP22

Gene Name		Rho GTPase activating protein 22
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Focal Adhesion
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated Small GTPase Mediated Signal Transduction Cell Differentiation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		Conduct disorder (case status) ( 20585324) Diabetic retinopathy ( 21310492) Self-employment ( 23593239)
Protein-protein Interactions		2 interactors: CACNA1A CCNDBP1
Entrez ID		58504
HPRD ID		12476
Ensembl ID		ENSG00000128805
Uniprot IDs		Q7Z5H3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cerebellar Molecular Layer Development Vestibular Nucleus Development Musculoskeletal Movement, Spinal Reflex Action Cerebellum Maturation Gamma-aminobutyric Acid Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Negative Regulation Of Hormone Biosynthetic Process Pons Development Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Reflex Behavioral Response To Pain Neuromuscular Synaptic Transmission Regulation Of Hormone Biosynthetic Process Cerebellar Cortex Formation Neurotransmitter Metabolic Process Gamma-aminobutyric Acid Signaling Pathway Cell Differentiation In Hindbrain Calcium Ion Import Regulation Of Hormone Metabolic Process Cerebellar Purkinje Cell Layer Development Membrane Depolarization During Action Potential Response To Pain Cerebellar Cortex Morphogenesis Synaptic Transmission, Glutamatergic Sulfur Amino Acid Metabolic Process Musculoskeletal Movement Calcium Ion-dependent Exocytosis Anion Homeostasis Spinal Cord Motor Neuron Differentiation Adult Walking Behavior Cerebellum Morphogenesis Receptor Clustering Neural Nucleus Development Hindbrain Morphogenesis Regulation Of Calcium Ion-dependent Exocytosis Transmission Of Nerve Impulse Ventral Spinal Cord Development Acid Secretion Cell Differentiation In Spinal Cord Cerebellar Cortex Development Regulation Of Neurotransmitter Secretion Neuron-neuron Synaptic Transmission Neuromuscular Process Controlling Balance Synapse Assembly
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