SRPRB

Name	SRP receptor subunit beta
Structure
Interactors	3 interactors: CDK5RAP3 RCHY1 UBC
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Membrane
	Molecular Function	Nucleotide Binding Protein Binding GTP Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Protein Targeting To ER
Pathways	SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes
GWAS	Alcohol consumption (transferrin glycosylation) ( 21665994 ) Mean corpuscular hemoglobin ( 29403010 32888494 ) Mean corpuscular volume ( 29403010 32888494 ) Nicotine dependence symptom count ( 25555482 ) Red blood cell count ( 32888494 )
Entrez ID	58477
HPRD ID	18105
Ensembl ID	ENSG00000144867
Uniprot IDs	Q549N5 Q9Y5M8
PDB IDs	7NFX
GO Terms Enriched among Interactors ?	Rescue Of Stalled Ribosome Ribosome Disassembly Protein Modification By Small Protein Conjugation Translational Elongation Organelle Disassembly Post-translational Protein Modification Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Regulation Of Post-translational Protein Modification Positive Regulation Of Reticulophagy Definitive Erythrocyte Differentiation Regulation Of Reticulophagy Protein Modification Process Error-free Translesion Synthesis Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Apoptotic Nuclear Changes Positive Regulation Of Protein Modification Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Protein Ufmylation Regulation Of Phosphatase Activity MDM2/MDM4 Family Protein Binding Protein Tag Activity Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of MAP Kinase Activity Protein Ubiquitination Mitogen-activated Protein Kinase Binding Regulation Of Protein Modification Process Regulation Of Dephosphorylation Translesion Synthesis Proteolysis Involved In Protein Catabolic Process Ubiquitin-like Protein Ligase Binding Protein Metabolic Process DNA Damage Response Postreplication Repair NF-kappaB Binding Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic G2 DNA Damage Checkpoint Signaling Cyclin Binding Negative Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Metabolic Process DNA Synthesis Involved In DNA Repair