WDR19

Description		WD repeat domain 19
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Cytoskeleton Plasma Membrane Cilium Intraciliary Transport Particle A Motile Cilium Photoreceptor Connecting Cilium Cell Projection Ciliary Tip Non-motile Cilium
	Molecular Function	Protein Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Smoothened Signaling Pathway Gonad Development Cell Projection Organization Embryonic Limb Morphogenesis Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Ear Morphogenesis Receptor Clustering Cilium Organization Embryonic Cranial Skeleton Morphogenesis Nervous System Process Digestive System Development Cilium Assembly Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Myotome Development Protein-containing Complex Assembly Protein Localization To Membrane Protein Localization To Ciliary Membrane
Pathways		Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases		Asphyxiating thoracic dystrophy; Jeune syndrome
GWAS		Cognitive function ( 24684796) Sensorimotor dexterity ( 31596458)
Interacting Genes		2 interacting genes: PTGER4 RIPK4
Entrez ID		57728
HPRD ID		10489
Ensembl ID		ENSG00000157796
Uniprot IDs		B4DGR6 Q8NEZ3
PDB IDs		8BBF 8BBG 8FGW 8FH3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Eosinophil Extravasation Negative Regulation Of Integrin Activation Negative Regulation Of Eosinophil Migration Prostaglandin Receptor Activity Prostaglandin E Receptor Activity Negative Regulation Of Cellular Extravasation Regulation Of Integrin Activation Cellular Response To Prostaglandin E Stimulus T-helper Cell Differentiation Regulation Of Cellular Extravasation Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E T Cell Differentiation Involved In Immune Response
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