WDR19

Name	WD repeat domain 19
Structure
Interactors	2 interactors: PTGER4 RIPK4
GO Annotations	Cellular Component	Photoreceptor Outer Segment Cytoplasm Cytoskeleton Plasma Membrane Cilium Intraciliary Transport Particle A Motile Cilium Photoreceptor Connecting Cilium Cell Projection Ciliary Tip Non-motile Cilium
	Molecular Function	Protein Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Smoothened Signaling Pathway Gonad Development Cell Projection Organization Embryonic Limb Morphogenesis Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Ear Morphogenesis Receptor Clustering Cilium Organization Embryonic Cranial Skeleton Morphogenesis Nervous System Process Digestive System Development Cilium Assembly Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Myotome Development Protein-containing Complex Assembly Protein Localization To Membrane Protein Localization To Ciliary Membrane
Pathways	Hedgehog 'off' state Intraflagellar transport
Diseases	Asphyxiating thoracic dystrophy; Jeune syndrome
GWAS	Cognitive function ( 24684796 ) Sensorimotor dexterity ( 31596458 )
Entrez ID	57728
HPRD ID	10489
Ensembl ID	ENSG00000157796
Uniprot IDs	B4DGR6 Q8NEZ3
PDB IDs	8BBF 8BBG 8FGW 8FH3
GO Terms Enriched among Interactors ?	Negative Regulation Of Eosinophil Extravasation Negative Regulation Of Integrin Activation Negative Regulation Of Eosinophil Migration Prostaglandin Receptor Activity Prostaglandin E Receptor Activity Negative Regulation Of Cellular Extravasation Regulation Of Integrin Activation Cellular Response To Prostaglandin E Stimulus T-helper Cell Differentiation Regulation Of Cellular Extravasation Cellular Response To Prostaglandin Stimulus Response To Prostaglandin E T Cell Differentiation Involved In Immune Response