PTH

Gene Name		parathyroid hormone
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Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Hormone Activity Parathyroid Hormone Receptor Binding Type 1 Parathyroid Hormone Receptor Binding Peptide Hormone Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Transcription From RNA Polymerase II Promoter Cellular Calcium Ion Homeostasis G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Rho Protein Signal Transduction Cell-cell Signaling Hormone-mediated Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Response To Lead Ion Regulation Of Gene Expression Positive Regulation Of Bone Mineralization Positive Regulation Of CAMP Biosynthetic Process Response To Vitamin D Cellular Macromolecule Biosynthetic Process Response To Drug Bone Resorption Response To Ethanol Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter CAMP Metabolic Process Positive Regulation Of Glucose Import Response To Cadmium Ion Response To Parathyroid Hormone Response To Fibroblast Growth Factor
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Bone mineral density ( 19874204)
Protein-protein Interactions		5 interactors: BAG6 FEZ1 MEP1A PTH1R PTH2R
Entrez ID		5741
HPRD ID		01345
Ensembl ID		ENSG00000152266
Uniprot IDs		P01270
PDB IDs		1BWX 1ET1 1ET2 1FVY 1HPH 1HPY 1HTH 1ZWA 1ZWB 1ZWD 1ZWE 1ZWF 1ZWG 2L1X 3C4M
Enriched GO Terms of Interacting Partners?
Tagcloud ?		accurately assay coefficients commercially cr1073m detectable determining egta example fifteen fragments gave gives immunoassay immunoreactive inter interfere interfered intra p55 parathyroid pg porcine proximity scintillation simply spa spiked throughput