PTGER2

Gene Name		prostaglandin E receptor 2 (subtype EP2), 53kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Prostaglandin E Receptor Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Response To Lipopolysaccharide Regulation Of Cell Proliferation Cellular Response To Prostaglandin E Stimulus
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Prostanoid ligand receptors Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding Eicosanoid ligand-binding receptors
Drugs		Alprostadil Dinoprostone Misoprostol
Diseases
GWAS
Protein-protein Interactions		3 interactors: PTGDS PTGES PTGFR
Entrez ID		5732
HPRD ID		08905
Ensembl ID		ENSG00000125384
Uniprot IDs		P43116
PDB IDs
Enriched GO Terms of Interacting Partners?		Cyclooxygenase Pathway Prostaglandin Biosynthetic Process Prostaglandin Metabolic Process Icosanoid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Arachidonic Acid Metabolic Process Response To Lipid Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Response To Lipopolysaccharide Fatty Acid Metabolic Process Response To Molecule Of Bacterial Origin Cellular Response To Prostaglandin D Stimulus Response To Bacterium Response To Organic Substance Calcium-mediated Signaling Using Intracellular Calcium Source Chronic Inflammatory Response Lipid Biosynthetic Process Monocarboxylic Acid Metabolic Process Regulation Of Circadian Sleep/wake Cycle, Sleep Parturition Cellular Response To Prostaglandin Stimulus Response To Other Organism Response To Biotic Stimulus Response To Organic Cyclic Compound Response To Hormone Cellular Lipid Metabolic Process Carboxylic Acid Metabolic Process Cellular Response To Fatty Acid Organic Acid Metabolic Process Lipid Metabolic Process Response To Fatty Acid Acute Inflammatory Response Regulation Of Cell Proliferation Calcium-mediated Signaling Regulation Of Circadian Rhythm Response To Calcium Ion Response To Retinoic Acid Response To External Stimulus Second-messenger-mediated Signaling Response To Glucocorticoid Response To Corticosteroid Cellular Response To Acid Chemical Regulation Of Behavior Small Molecule Metabolic Process
Tagcloud ?		appeared deltadeltact diestrus endometrium ep2 ep4 equine esr1 esr2 estrus glands immunolabeling immunoreactivity immunostaining intense localize mares myometrium pgr pr pregnancy prostaglandin qpcr quantified reproductive stroma tended weak