OTUD7B

Gene Name		OTU deubiquitinase 7B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	DNA Binding Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Zinc Ion Binding K63-linked Polyubiquitin Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Mucosal Immune Response Proteolysis Negative Regulation Of Interleukin-8 Production Protein K11-linked Deubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		4 interactors: TRAF6 UBC UBE2S ZDHHC17
Entrez ID		56957
HPRD ID		10313
Ensembl ID
Uniprot IDs		Q6GQQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Ubiquitination Protein Polyubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Protein Ubiquitination Regulation Of I-kappaB Kinase/NF-kappaB Signaling Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Protein K63-linked Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Transferase Activity MyD88-dependent Toll-like Receptor Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Protein Ubiquitination Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Protein Modification By Small Protein Conjugation JNK Cascade Regulation Of Ubiquitin-protein Transferase Activity Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Antigen Receptor-mediated Signaling Pathway Activation Of MAPK Activity Activation Of Innate Immune Response Positive Regulation Of Protein Modification Process Free Ubiquitin Chain Polymerization Positive Regulation Of Innate Immune Response Cellular Protein Modification Process Positive Regulation Of Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway
Tagcloud ?		accumulating antitumor atra clusters consensus decreases derivatives epidemiological est exert facilitating hcc hepatocellular hepg2 huh7 kb mcf7 negatively organs ra rares responsive retinoic retinoid retinoids silico upstream