MRPS22

Description		mitochondrial ribosomal protein S22
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Structural Constituent Of Ribosome Protein Binding
	Biological Process	Mitochondrial Translation
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases		Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Ear morphology ( 26105758) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Lobe size ( 26105758) Male-pattern baldness ( 27182965) Obesity-related traits ( 22013104 23251661) Offspring birth weight ( 31043758) Rosacea symptom severity ( 29771307)
Interacting Genes		7 interacting genes: BARD1 BTK ERCC6 PTEN SHD SUMO4 UBC
Entrez ID		56945
HPRD ID		10430
Ensembl ID		ENSG00000175110
Uniprot IDs		A0A7P0MKV3 P82650
PDB IDs		3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		Protein Modification Process Protein Tag Activity Negative Regulation Of Cell Cycle Phase Transition Protein Modification By Small Protein Conjugation Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Cell Cycle Process Protein Metabolic Process Post-translational Protein Modification Negative Regulation Of Cell Cycle Negative Regulation Of MRNA 3'-end Processing Regulation Of B Cell Cytokine Production Monocyte Proliferation Positive Regulation Of Interleukin-17A Production Response To Oxidative Stress Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Phosphorylation Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity Regulation Of Cell Cycle Phase Transition BRCA1-BARD1 Complex Positive Regulation Of Type I Hypersensitivity B Cell Affinity Maturation Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Regulation Of Phosphorus Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Eosinophil Homeostasis Positive Regulation Of Type III Hypersensitivity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission BRCA1-B Complex Response To Ionizing Radiation Protein Ubiquitination Positive Regulation Of Synoviocyte Proliferation Cellular Response To Molecule Of Fungal Origin Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells SUMO Ligase Complex Negative Regulation Of Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To Stress Histamine Secretion By Mast Cell Response To Reactive Oxygen Species Response To Molecule Of Fungal Origin Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Positive Regulation Of Protein Metabolic Process
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