PAG1

Gene Name		phosphoprotein membrane anchor with glycosphingolipid microdomains 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Membrane Raft
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH2 Domain Binding
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Intracellular Signal Transduction T Cell Receptor Signaling Pathway Regulation Of T Cell Activation Negative Regulation Of T Cell Activation
Pathways		Signaling by EGFR TCR signaling GAB1 signalosome Signaling by EGFR in Cancer Signaling by Ligand-Responsive EGFR Variants in Cancer Signaling by EGFRvIII in Cancer Signaling by Overexpressed Wild-Type EGFR in Cancer Phosphorylation of CD3 and TCR zeta chains Adaptive Immune System
Drugs
Diseases
GWAS		Serum total protein level ( 23022100)
Protein-protein Interactions		17 interactors: ABL1 CSK FYN GLS2 GRB2 HTRA2 LCK LCP2 LYN PTPN11 PTPN6 RASA1 SHC1 SLC9A3R1 SYK VAV1 ZAP70
Entrez ID		55824
HPRD ID		05772
Ensembl ID		ENSG00000076641
Uniprot IDs		Q9NWQ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Blood Coagulation Immune Response-activating Cell Surface Receptor Signaling Pathway Hemostasis Enzyme Linked Receptor Protein Signaling Pathway Platelet Activation Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Leukocyte Migration Antigen Receptor-mediated Signaling Pathway Regulation Of Cell-cell Adhesion Innate Immune Response T Cell Costimulation Positive Regulation Of Cell-cell Adhesion Regulation Of Body Fluid Levels Peptidyl-tyrosine Autophosphorylation Wound Healing Regulation Of Immune Response Regulation Of Cell Adhesion Fc Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of T Cell Activation Cell Activation Positive Regulation Of Cell Activation Response To Wounding Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Cell Migration Regulation Of Lymphocyte Activation Cell Motility Positive Regulation Of Immune System Process Locomotion Positive Regulation Of Signal Transduction Positive Regulation Of Immune Response Peptidyl-tyrosine Phosphorylation Immune Response Regulation Of Immune System Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Defense Response Regulation Of Cell Activation Movement Of Cell Or Subcellular Component Positive Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cellular Response To Organonitrogen Compound Intracellular Signal Transduction
Tagcloud ?		adaptor cbp cpg deacetylase egf epigenetic h4 harboring hdac hdac1 hypomethylation inactivation inhibiting inversely islands mapk mek modifications oncogenic pi3k restored src subset suppressed suppressor transformation transformed transmembrane trimethylation