SMPD4

Gene Name		sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Integral Component Of Membrane
	Molecular Function	Sphingomyelin Phosphodiesterase Activity Metal Ion Binding Sphingomyelin Phosphodiesterase D Activity
	Biological Process	Sphingolipid Metabolic Process Sphingomyelin Catabolic Process Glycosphingolipid Metabolic Process Small Molecule Metabolic Process Glycerophospholipid Catabolic Process Ceramide Biosynthetic Process Cellular Response To Tumor Necrosis Factor
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Glycosphingolipid metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: EXOSC4
Entrez ID		55627
HPRD ID		13374
Ensembl ID		ENSG00000136699
Uniprot IDs		B1PBA3 B4DM23 B4DQ31 B4DWK7 B4E0L6 H7BXF4 Q9NXE4
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear MRNA Surveillance RNA Surveillance DNA Deamination Histone MRNA Catabolic Process Maturation Of 5.8S RRNA Histone MRNA Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay DNA Modification RNA Phosphodiester Bond Hydrolysis Positive Regulation Of Cell Growth RRNA Processing RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Defense Response To Virus RNA Catabolic Process Ribosome Biogenesis Positive Regulation Of Growth Response To Virus Nucleic Acid Phosphodiester Bond Hydrolysis Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Aromatic Compound Catabolic Process NcRNA Metabolic Process MRNA Metabolic Process Regulation Of Growth
Tagcloud ?		atrophy c2c12 connection cytosol detergent differently doublet exon fractionates innovation isoform kd links muscles myotube myotubes nsmase nsmase3 nsmase3a nsmase3b oxidant partition readily resides sarcolemmal skeletal sphingolipid sphingomyelinase striated