AMBRA1

Gene Name		autophagy/beclin-1 regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Autophagic Vacuole Cytosol Axoneme Intracellular Membrane-bounded Organelle Phagocytic Vesicle
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Autophagy Negative Regulation Of Cell Proliferation Neural Tube Development Cell Differentiation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Mitochondrion Degradation Regulation Of Autophagic Vacuole Assembly
Pathways
Drugs
Diseases
GWAS		Immunoglobulin A ( 20694011)
Protein-protein Interactions		5 interactors: BECN1 DYNLL1 MTOR RNF2 UBE2D3
Entrez ID		55626
HPRD ID		10975
Ensembl ID		ENSG00000110497
Uniprot IDs		Q9C0C7
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Hypoxia Protein Monoubiquitination Positive Regulation Of Organelle Organization Positive Regulation Of Mitochondrion Organization Cellular Response To Growth Factor Stimulus Regulation Of Mitochondrion Organization Response To Growth Factor Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Autophagy Cellular Response To Aluminum Ion Regulation Of Carbohydrate Utilization Cellular Response To Oxygen Levels Negative Regulation Of Cellular Metabolic Process Immune System Process Positive Regulation Of Mitochondrion Degradation CVT Pathway Histone H2A-K119 Monoubiquitination Cellular Nitrogen Compound Metabolic Process Regulation Of Organelle Organization Cellular Response To Nutrient Levels Nitrogen Compound Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Response To Abiotic Stimulus Response To Aluminum Ion Late Endosome To Vacuole Transport Negative Regulation Of NFAT Protein Import Into Nucleus Defense Response Cell Cycle Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Mitochondrion Degradation Histone H2A Monoubiquitination Cellular Response To Stress Negative Regulation Of Macroautophagy Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Macroautophagy Histone H2A Ubiquitination Response To Nutrient Levels Negative Regulation Of Cell Size Regulation Of Metabolic Process Regulation Of Intracellular Transport Regulation Of Fatty Acid Beta-oxidation Cellular Response To Nitrogen Starvation Positive Regulation Of Lamellipodium Organization Response To Extracellular Stimulus Regulation Of Response To Food Immune Response-regulating Signaling Pathway Catabolic Process Response To Vitamin E
Tagcloud ?		aldrich arp2 associates autophagy becn1 cul4a ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates rnf2 scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott