PPP6R3

Description		protein phosphatase 6 regulatory subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase Binding
	Biological Process	Regulation Of Signal Transduction
Pathways		Telomere Extension By Telomerase COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 28743860) Femoral neck section modulus ( 30888730) Fractures ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Monobrow ( 27182965) QT interval ( 29213071) Serum metabolite levels ( 33031748)
Interacting Genes		6 interacting genes: LATS1 PRKDC TERF2IP TINF2 UBC YWHAG
Entrez ID		55291
HPRD ID		10703
Ensembl ID		ENSG00000110075
Uniprot IDs		E9PKF6 H7BXH2 Q5H9R7
PDB IDs
Enriched GO Terms of Interacting Partners?		Telomere Capping Negative Regulation Of Phosphorylation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Phosphate Metabolic Process Shelterin Complex Chromosome Organization Regulation Of Protein Phosphorylation Telomere Maintenance Nuclear Telomere Cap Complex Protein Localization To Chromosome Regulation Of Phosphorylation Protein Localization To Chromosome, Telomeric Region Telomere Organization Regulation Of Phosphorus Metabolic Process Negative Regulation Of Protein Metabolic Process Chromosome, Telomeric Region Protein Localization To Organelle Regulation Of Protein Modification Process Telomeric DNA Binding Intracellular Protein Localization Negative Regulation Of Telomere Maintenance Positive Regulation Of DNA Metabolic Process Negative Regulation Of Protein Kinase Activity Positive Regulation Of Telomere Maintenance Negative Regulation Of Kinase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Macromolecule Metabolic Process Regulation Of DNA Metabolic Process Cellular Response To Insulin Stimulus Macromolecule Metabolic Process Positive Regulation Of Chromosome Organization Negative Regulation Of Metabolic Process Regulation Of Telomere Maintenance Positive Regulation Of Platelet Formation Perinucleolar Chromocenter Negative Regulation Of DNA Recombination At Telomere Regulation Of Protein Metabolic Process Protein Modification Process DNA-dependent Protein Kinase Activity Small-subunit Processome Assembly Histone H2AXS139 Kinase Activity Protein Kinase C Inhibitor Activity Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Negative Regulation Of DNA Metabolic Process Regulation Of Double-strand Break Repair Positive Regulation Of Translation Pro-B Cell Differentiation Response To Insulin T Cell Receptor V(D)J Recombination
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