PCSK4

Description		proprotein convertase subtilisin/kexin type 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Acrosomal Membrane Trans-Golgi Network Membrane Cytoplasmic Vesicle
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Binding Of Sperm To Zona Pellucida Acrosome Reaction Fertilization Protein Processing Peptide Hormone Processing Reproductive Process Sperm Capacitation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: ASPH FOXP1 IGF2
Entrez ID		54760
HPRD ID		06773
Ensembl ID		ENSG00000115257
Uniprot IDs		A0A140VJQ9 Q6UW60
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Organ Growth Negative Regulation Of Muscle Cell Differentiation Activation Of Store-operated Calcium Channel Activity Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Store-operated Calcium Channel Activity Regulation Of Cell Population Proliferation Regulation Of Muscle System Process Regulation Of Muscle Cell Differentiation Positive Regulation Of Skeletal Muscle Tissue Growth Regulation Of Developmental Growth Regulation Of Skeletal Muscle Tissue Growth Embryonic Placenta Morphogenesis Positive Regulation Of Interleukin-21 Production Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Osteoclast Development Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Endothelial Tube Morphogenesis Cortical Endoplasmic Reticulum Positive Regulation Of B Cell Receptor Signaling Pathway Sarcoplasmic Reticulum Lumen Junctional Sarcoplasmic Reticulum Membrane Exocrine Pancreas Development Monocyte Activation Endothelial Cell Activation Positive Regulation Of Biosynthetic Process Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Cell Communication By Electrical Coupling Regulation Of Cellular Component Organization Regulation Of Calcium Ion Transport Into Cytosol Detection Of Calcium Ion Regulation Of System Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Striated Muscle Tissue Development Transmembrane Receptor Protein Tyrosine Kinase Activator Activity Regulation Of Growth Positive Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Glycogen Biosynthetic Process Insulin-like Growth Factor Receptor Binding Positive Regulation Of Skeletal Muscle Tissue Development Genomic Imprinting Positive Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Defense Response To Bacterium Negative Regulation Of B Cell Apoptotic Process Negative Regulation Of Androgen Receptor Signaling Pathway Striatum Development Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Monocyte Differentiation T Follicular Helper Cell Differentiation
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