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POLR2I
Description
RNA polymerase II subunit I
Image
GO Annotations
Cellular Component
DNA-directed RNA Polymerase Complex
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Nucleolus
Molecular Function
Nucleic Acid Binding
DNA-directed RNA Polymerase Activity
Protein Binding
Zinc Ion Binding
Metal Ion Binding
Biological Process
Maintenance Of Transcriptional Fidelity During Transcription Elongation By RNA Polymerase II
Transcription-coupled Nucleotide-excision Repair
DNA-templated Transcription
Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Diseases
GWAS
Novel Interacting Genes
1 novel interacting genes:
ZNF536
Interacting Genes
2 interacting genes:
POLR2H
TBCD
Entrez ID
5438
HPRD ID
15944
Ensembl ID
ENSG00000105258
Uniprot IDs
P36954
PDB IDs
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6DRD
6O9L
6XRE
7LBM
9EHZ
9EI1
9EI3
9EI4
Enriched GO Terms of Interacting Partners
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RNA Polymerase III Complex
RNA Polymerase I Complex
RNA Polymerase II, Core Complex
Adherens Junction Assembly
Negative Regulation Of Microtubule Polymerization
Post-chaperonin Tubulin Folding Pathway
Tubulin Complex Assembly
Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
Retinoic Acid-responsive Element Binding
Regulation Of Retinoic Acid Receptor Signaling Pathway
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