CPSF2

Gene Name		cleavage and polyadenylation specific factor 2, 100kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Membrane
	Molecular Function	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage Histone MRNA 3'-end Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Transport of Mature mRNA Derived from an Intronless Transcript RNA Polymerase II Transcription Transport of Mature mRNAs Derived from Intronless Transcripts Cleavage of Growing Transcript in the Termination Region mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Intronless Pre-mRNAs Processing of Capped Intronless Pre-mRNA Transport of Mature Transcript to Cytoplasm RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Dialysis-related mortality ( 21546767) Height ( 18391951) Obesity-related traits ( 23251661)
Protein-protein Interactions		2 interactors: POLR2A WWOX
Entrez ID		53981
HPRD ID		05824
Ensembl ID		ENSG00000165934
Uniprot IDs		Q9P2I0
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, RNA-templated 7-methylguanosine MRNA Capping PiRNA Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of RNA Splicing 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Nucleotide-excision Repair Regulation Of RNA Splicing Extrinsic Apoptotic Signaling Pathway
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