PMS1

Gene Name		PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
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Gene Ontology Annotations	Cellular Component	Nucleus MutLalpha Complex
	Molecular Function	DNA Binding Single-stranded DNA Binding ATP Binding ATPase Activity Mismatched DNA Binding
	Biological Process	Mismatch Repair Response To Drug
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Subcutaneous adipose tissue ( 22589738)
Protein-protein Interactions		1 interactors: MLH1
Entrez ID		5378
HPRD ID		02597
Ensembl ID		ENSG00000064933
Uniprot IDs		B4DMF4 P54277
PDB IDs		2CS1
Enriched GO Terms of Interacting Partners?		Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Negative Regulation Of Mitotic Recombination Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Spindle Midzone Assembly Resolution Of Meiotic Recombination Intermediates Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Double-strand Break Repair Via Nonhomologous End Joining Chromosome Separation Negative Regulation Of DNA Recombination Nuclear-transcribed MRNA Poly(A) Tail Shortening Isotype Switching Metaphase Plate Congression Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Establishment Of Chromosome Localization Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Reciprocal Meiotic Recombination B Cell Activation Involved In Immune Response Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Synapsis Mismatch Repair Homologous Chromosome Segregation Male Meiosis Immunoglobulin Production Regulation Of DNA Recombination Oogenesis MRNA 3'-end Processing Meiotic Chromosome Segregation Spindle Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of DNA Metabolic Process RNA 3'-end Processing Meiosis I Female Gamete Generation Spindle Organization Nuclear-transcribed MRNA Catabolic Process Double-strand Break Repair Leukocyte Activation Involved In Immune Response B Cell Activation MRNA Catabolic Process Meiotic Nuclear Division Immunoglobulin Mediated Immune Response B Cell Mediated Immunity RNA Catabolic Process Intrinsic Apoptotic Signaling Pathway Meiotic Cell Cycle Chromosome Segregation
Tagcloud ?		abnormally angiogenesis antiapoptotic carcinomas colon division enhances immunoreaction immunostaining inactivated inactivation intensity labeled mismatch mlh1 mmr mmrp msh2 msh6 pms2 polyp polyps powerful predominantly rarely repair section suppress survivin