PIGC

Gene Name		phosphatidylinositol glycan anchor biosynthesis, class C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Catalytic Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	C-terminal Protein Lipidation GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI) Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Waist-hip ratio ( 20935629)
Protein-protein Interactions		4 interactors: DPM2 KLF10 PIGQ ZHX1
Entrez ID		5279
HPRD ID		03433
Ensembl ID		ENSG00000135845
Uniprot IDs		Q92535
PDB IDs
Enriched GO Terms of Interacting Partners?		Preassembly Of GPI Anchor In ER Membrane C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Cellular Macromolecule Biosynthetic Process Phospholipid Biosynthetic Process Macromolecule Biosynthetic Process Dolichol Metabolic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Biosynthetic Process Protein O-linked Mannosylation Protein Mannosylation Lipid Biosynthetic Process Positive Regulation Of Osteoclast Differentiation Mannosylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Bone Mineralization Positive Regulation Of Myeloid Leukocyte Differentiation Dolichol-linked Oligosaccharide Biosynthetic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Carbohydrate Metabolic Process Regulation Of Osteoclast Differentiation Somatic Stem Cell Maintenance Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Myeloid Cell Differentiation Biomineral Tissue Development Protein O-linked Glycosylation Lipid Metabolic Process Regulation Of Circadian Rhythm Protein N-linked Glycosylation Via Asparagine Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process
Tagcloud ?		1q24 200k aaa adventitial aneurysm aortic atherosclerosis atherosclerotic c1orf105 carotid cimt cohorts compensatory determinants dnm3 enlargement expansive forward iccad illumina intima metabochip pooling proxy q remodelling rs3768445 rs4916251 snp