PEX14

Gene Name		peroxisomal biogenesis factor 14
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Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Nucleolus Peroxisome Peroxisomal Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Protein Complex
	Molecular Function	Transcription Corepressor Activity Receptor Binding Protein Binding Microtubule Binding Protein N-terminus Binding Beta-tubulin Binding
	Biological Process	Protein Complex Assembly Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Translocation Negative Regulation Of Protein Binding Microtubule Anchoring Peroxisome Transport Along Microtubule Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Import Into Peroxisome Matrix, Substrate Release Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization Negative Regulation Of Protein Homotetramerization
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729 23535733) Optic disc size (rim) ( 20395239)
Protein-protein Interactions		8 interactors: HDAC1 MED8 NFE2 PEX19 PEX5 PEX7 SMARCC2 ZHX1
Entrez ID		5195
HPRD ID		03477
Ensembl ID		ENSG00000142655
Uniprot IDs		F5H4J2 O75381
PDB IDs		2W84 2W85
Enriched GO Terms of Interacting Partners?		Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Protein Import Into Peroxisome Membrane Peroxisomal Membrane Transport Protein Import Into Peroxisome Matrix Nucleosome Disassembly Protein Import Fatty Acid Beta-oxidation Organelle Organization Regulation Of Transcription From RNA Polymerase II Promoter Establishment Of Protein Localization To Organelle Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process ATP-dependent Chromatin Remodeling Protein Targeting Negative Regulation Of Lipid Binding Transcription, DNA-templated RNA Biosynthetic Process Protein Localization To Organelle Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Nucleosome Organization Cellular Lipid Catabolic Process Chromatin Assembly Or Disassembly Cellular Metabolic Process Cytoplasmic Transport Organ Development Protein Targeting To Membrane Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix, Docking Neuron Migration Biosynthetic Process Chromatin Organization Transcription Initiation From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Chromatin Remodeling Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Lipid Modification Carboxylic Acid Catabolic Process Negative Regulation Of Protein Homooligomerization Ether Lipid Biosynthetic Process Protein Complex Disassembly Central Nervous System Neuron Differentiation Cell Differentiation
Tagcloud ?		aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex11 pex28 pex3 pex5 pex6 pex7 pex8 pox1 puf5 rbp rfp