CDK12

Gene Name		cyclin-dependent kinase 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cyclin K-CDK12 Complex Nucleus Nucleoplasm Nucleolus Nuclear Speck Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex
	Molecular Function	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding RNA Polymerase II Carboxy-terminal Domain Kinase Activity Cyclin Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of MAP Kinase Activity Protein Autophosphorylation Regulation Of Cell Cycle Phosphorylation Of RNA Polymerase II C-terminal Domain
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: EWSR1 MBP PIN1 POLR2A PRPF40A SRSF1 SRSF2
Entrez ID		51755
HPRD ID		10849
Ensembl ID		ENSG00000167258
Uniprot IDs		Q9NYV4
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Regulation Of Cytokinesis MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Regulation Of RNA Splicing RNA 3'-end Processing Nuclear Export MRNA Transport Transcription, RNA-templated RNA Transport RNA Metabolic Process RNA Localization Defense Response To Nematode Gene Expression MRNA 5'-splice Site Recognition Transcription From RNA Polymerase II Promoter Negative Regulation Of Cytokine Production Response To Nematode Regulation Of Cell Division Transcription, DNA-templated Nucleocytoplasmic Transport Nuclear Transport RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Interleukin-10 Production Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Cis Splicing, Via Spliceosome Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Interleukin-4 Production Response To Mercury Ion Regulation Of Cell Morphogenesis Regulation Of Cellular Process Regulation Of Cell Cycle Process Nitrogen Compound Metabolic Process 7-methylguanosine MRNA Capping Regulation Of Interleukin-4 Production PiRNA Metabolic Process Regulation Of Cytokine Production Positive Regulation Of RNA Splicing 7-methylguanosine RNA Capping Substantia Nigra Development
Tagcloud ?		affects associate bulk ccnk cdk13 cdk9 cdks ctd elongation far flag hct116 heptad implementing numerous paralog partner phosphorylate preferentially processing repeat reveals rna sec seq snorna super tagged tefb