PDYN

Gene Name		prodynorphin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane
	Molecular Function	Opioid Peptide Activity
	Biological Process	Neuropeptide Signaling Pathway Synaptic Transmission
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors G-protein activation Class A/1 (Rhodopsin-like receptors) Opioid Signalling G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Immune response to smallpox vaccine (IL-6) ( 22542470)
Protein-protein Interactions		2 interactors: APP NRD1
Entrez ID		5173
HPRD ID		08838
Ensembl ID		ENSG00000101327
Uniprot IDs		P01213
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuromuscular Junction Development Synapse Organization Synaptic Growth At Neuromuscular Junction Positive Regulation Of Proteolysis Collateral Sprouting In Absence Of Injury Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Regulation Of Proteolysis Positive Regulation Of Membrane Protein Ectodomain Proteolysis Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of Protein Metabolic Process Mating Behavior Locomotion Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Movement Of Cell Or Subcellular Component Axon Cargo Transport Mating Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		aceh3k9 ana ascending bdnf bni cessation dynorphin hdac horn hydroxamic hyperalgesia hypersensitivity immuoprecipation lastly lysine9 maladaptations morphine neurotrophic oih opioid opioids prodynorphin prolongation resolves saha seeks suberoylanilide trkb tropomyosin