PDK4

Gene Name		pyruvate dehydrogenase kinase, isozyme 4
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Protein Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity ATP Binding
	Biological Process	Glucose Metabolic Process Pyruvate Metabolic Process Protein Phosphorylation Regulation Of PH Insulin Receptor Signaling Pathway Cellular Response To Starvation Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Regulation Of Cellular Ketone Metabolic Process Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Glucose Homeostasis Response To Starvation Cellular Metabolic Process Small Molecule Metabolic Process Regulation Of Bone Resorption Regulation Of Fatty Acid Oxidation Cellular Response To Fatty Acid Reactive Oxygen Species Metabolic Process Negative Regulation Of Anoikis
Pathways		Regulation of pyruvate dehydrogenase (PDH) complex Pyruvate metabolism Signaling by Retinoic Acid Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: DLAT PDHA1 TRIM63
Entrez ID		5166
HPRD ID		03957
Ensembl ID		ENSG00000004799
Uniprot IDs		A4D1H4 Q16654
PDB IDs		2E0A 2ZDX 2ZDY 2ZKJ 3D2R
Enriched GO Terms of Interacting Partners?		Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Regulation Of Acyl-CoA Biosynthetic Process Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Regulation Of Fatty Acid Metabolic Process Pyruvate Metabolic Process Glucose Metabolic Process Cellular Respiration Hexose Metabolic Process Monosaccharide Metabolic Process Acetyl-CoA Biosynthetic Process From Pyruvate Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Lipid Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Skeletal Muscle Atrophy Striated Muscle Atrophy Acetyl-CoA Biosynthetic Process Muscle Atrophy Generation Of Precursor Metabolites And Energy Skeletal Muscle Adaptation Regulation Of Cellular Ketone Metabolic Process Monocarboxylic Acid Metabolic Process Acetyl-CoA Metabolic Process Cellular Response To Dexamethasone Stimulus Response To Dexamethasone Carboxylic Acid Metabolic Process Response To Electrical Stimulus Carbohydrate Metabolic Process Cellular Response To Glucocorticoid Stimulus Organic Acid Metabolic Process Cellular Response To Corticosteroid Stimulus Acyl-CoA Metabolic Process Response To Interleukin-1 Regulation Of Phosphorus Metabolic Process Oxidation-reduction Process Glycolytic Process Catabolic Process Coenzyme Biosynthetic Process Carbohydrate Catabolic Process Response To Glucocorticoid Response To Corticosteroid Cellular Response To Steroid Hormone Stimulus
Tagcloud ?		bioinformatic desaturation diabesity discriminant dock1 elutriated ether fam126a gnptab goes granulocytes klf4 lipidome lipidomic monocyte mufa nfy pe peroxisomal phagocytic plasmalogen plasmalogens pls pufa rhm rnf96 silico squares transcriptomic