DPH5

Description		diphthamide biosynthesis 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Methyltransferase Activity Transferase Activity Diphthine Methyl Ester Synthase Activity
	Biological Process	Protein Histidyl Modification To Diphthamide Methylation
Pathways		Synthesis of diphthamide-EEF2
Drugs		S-adenosyl-L-homocysteine
Diseases
GWAS		Irritable bowel syndrome ( 29673008) QT interval (drug interaction) ( 23459443)
Novel Interacting Genes		3 novel interacting genes: RUSC1 SLC30A7 SLC71A1
Interacting Genes
Entrez ID		51611
HPRD ID		13037
Ensembl ID		ENSG00000117543
Uniprot IDs		B3KWP1 Q9H2P9
PDB IDs
Enriched GO Terms of Interacting Partners?		Sperm Mitochondrion Organization Golgi Cis Cisterna Membrane Zinc Ion Import Into Golgi Lumen Spermatid Nucleus Differentiation Zinc Ion Import Into Organelle Monoatomic Cation Transmembrane Transporter Activity Acrosome Assembly Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Cytoplasmic Vesicle Sarcoplasmic Reticulum Membrane
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