IL23A

Gene Name		interleukin 23, alpha subunit p19
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Gene Ontology Annotations	Cellular Component	Interleukin-23 Complex
	Molecular Function	Cytokine Activity Protein Binding Interleukin-23 Receptor Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Defense Response To Virus By Host Positive Regulation Of T-helper 1 Type Immune Response Inflammatory Response Positive Regulation Of Activation Of JAK2 Kinase Activity Negative Regulation Of Interleukin-10 Production Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-17 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Natural Killer Cell Activation Positive Regulation Of Natural Killer Cell Proliferation Positive Regulation Of Tissue Remodeling T Cell Proliferation Positive Regulation Of T Cell Proliferation Positive Regulation Of Activated T Cell Proliferation Positive Regulation Of NF-kappaB Import Into Nucleus Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Positive Regulation Of Tyrosine Phosphorylation Of Stat4 Protein Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Positive Regulation Of Memory T Cell Differentiation Innate Immune Response Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Tissue Remodeling Positive Regulation Of Inflammatory Response Defense Response To Gram-negative Bacterium Positive Regulation Of NK T Cell Activation Positive Regulation Of NK T Cell Proliferation Defense Response To Virus Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of T-helper 17 Type Immune Response Positive Regulation Of T-helper 17 Cell Lineage Commitment
Pathways
Drugs
Diseases
GWAS		Psoriasis ( 20953190 19169254)
Protein-protein Interactions		3 interactors: IL12RB1 IL23R PEX19
Entrez ID		51561
HPRD ID		12026
Ensembl ID		ENSG00000110944
Uniprot IDs		Q9NPF7
PDB IDs		3D85 3D87 3DUH 3QWR
Enriched GO Terms of Interacting Partners?		Interleukin-23-mediated Signaling Pathway Positive Regulation Of T-helper 17 Cell Lineage Commitment Positive Regulation Of Memory T Cell Differentiation Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Memory T Cell Differentiation Positive Regulation Of T-helper 1 Type Immune Response Positive Regulation Of Cell Fate Commitment Positive Regulation Of Defense Response To Virus By Host Positive Regulation Of Activated T Cell Proliferation Positive Regulation Of T-helper Cell Differentiation Regulation Of Defense Response To Virus By Host Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Cell Fate Commitment Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper Cell Differentiation Regulation Of Activated T Cell Proliferation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Alpha-beta T Cell Differentiation Positive Regulation Of Interferon-gamma Production Regulation Of Defense Response To Virus Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Differentiation Positive Regulation Of T Cell Mediated Cytotoxicity Regulation Of Interferon-gamma Production Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Regulation Of T Cell Differentiation Regulation Of T Cell Proliferation Positive Regulation Of Adaptive Immune Response Negative Regulation Of Lipid Binding Regulation Of Lymphocyte Differentiation Response To Interferon-gamma Regulation Of Adaptive Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Interleukin-12-mediated Signaling Pathway Regulation Of T Cell Activation Peroxisome Membrane Biogenesis Positive Regulation Of Tyrosine Phosphorylation Of Stat4 Protein Positive Regulation Of Cell Activation Positive Regulation Of NK T Cell Activation Response To Interleukin-12 Positive Regulation Of Activation Of JAK2 Kinase Activity
Tagcloud ?		acidophilus ccl22 ccl3 ccl4 cd5 cd80 cd86 cocultivation crlf2 csf2ra cxcl11 dqa1 hivep2 icam1 ido1 il15ra il1a il1b il2ra il6 il7r il8 lactobacillus nfkb1 nfkb2 probiotic relb thp tlr7