SCLY

Description		selenocysteine lyase
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Catalytic Complex
	Molecular Function	Protein Binding Selenocysteine Lyase Activity Amino Acid Binding Transferase Activity Lyase Activity Protein Homodimerization Activity Vitamin B6 Binding
	Biological Process	Amino Acid Metabolic Process Selenocysteine Catabolic Process
Pathways		Metabolism of ingested SeMet, Sec, MeSec into H2Se
Drugs		Pyridoxal phosphate Pyridoxal phosphate
Diseases
GWAS
Interacting Genes		5 interacting genes: CREB3 LNX2 OGT SEPHS2 TERF2IP
Entrez ID		51540
HPRD ID		15303
Ensembl ID		ENSG00000132330
Uniprot IDs		A0A0A0MQU4 B4DDP9 Q59FK2 Q96I15
PDB IDs		3GZC 3GZD
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Deacetylase Activity Selenocysteine Biosynthetic Process Selenide, Water Dikinase Activity Selenium Compound Metabolic Process Negative Regulation Of DNA Recombination At Telomere Protein O-acetylglucosaminyltransferase Activity Selenocysteine Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose CCR1 Chemokine Receptor Binding Release From Viral Latency Protection From Non-homologous End Joining At Telomere Shelterin Complex Regulation Of Transcription By Glucose Nuclear Telomere Cap Complex CAMP Response Element Binding Protein Binding G-rich Strand Telomeric DNA Binding NSL Complex Protein Localization To Chromosome, Telomeric Region
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