PDE1B

Gene Name		phosphodiesterase 1B, calmodulin-dependent
Image
Gene Ontology Annotations	Cellular Component	Cytosol Neuronal Cell Body
	Molecular Function	3',5'-cyclic-AMP Phosphodiesterase Activity Calmodulin-dependent Cyclic-nucleotide Phosphodiesterase Activity Calmodulin Binding Metal Ion Binding Calcium- And Calmodulin-regulated 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Regulation Of Neurotransmitter Levels Response To Amphetamine CAMP Catabolic Process Apoptotic Process Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Activation Of Phospholipase C Activity Blood Coagulation Locomotory Behavior Visual Learning Fibroblast Growth Factor Receptor Signaling Pathway Monocyte Differentiation Cellular Response To Macrophage Colony-stimulating Factor Stimulus Regulation Of Dopamine Metabolic Process Serotonin Metabolic Process Innate Immune Response CGMP Catabolic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Pathways		Ca-dependent events Signaling by GPCR CaM pathway Signaling by FGFR in disease Phospholipase C-mediated cascade G alpha (s) signalling events Cam-PDE 1 activation cGMP effects Signaling by EGFRvIII in Cancer PLCG1 events in ERBB2 signaling DAG and IP3 signaling DAP12 signaling CaM pathway Downstream signaling of activated FGFR Nitric oxide stimulates guanylate cyclase Innate Immune System Signaling by PDGF Calmodulin induced events DAP12 interactions Signalling by NGF PLC beta mediated events Opioid Signalling Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane G-protein mediated events Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR EGFR interacts with phospholipase C-gamma Signaling by ERBB2 Cam-PDE 1 activation Signaling by EGFR GPCR downstream signaling Platelet homeostasis Downstream signal transduction Calmodulin induced events PLC-gamma1 signalling Signaling by EGFR in Cancer
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: POT1 UBE3A
Entrez ID		5153
HPRD ID		01388
Ensembl ID		ENSG00000123360
Uniprot IDs		B4DK72 Q01064 Q7Z364
PDB IDs		1LXR 1TAZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Strand Elongation Sperm Entry Telomere Formation Via Telomerase Positive Regulation Of Helicase Activity Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Prostate Gland Growth RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Protein K48-linked Ubiquitination Androgen Receptor Signaling Pathway Protein Autoubiquitination Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of DNA Replication Telomere Maintenance Ovarian Follicle Development Prostate Gland Development Intracellular Steroid Hormone Receptor Signaling Pathway DNA Duplex Unwinding DNA Geometric Change Negative Regulation Of Chromosome Organization Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Circadian Rhythm Negative Regulation Of DNA Metabolic Process Ovulation Cycle Process Organ Growth Female Gonad Development Ovulation Cycle Development Of Primary Female Sexual Characteristics Regulation Of DNA Replication Single Fertilization Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		adjust adora2a avp cart cecal clp gng7 intramuscular ku myh7 oxt pdyn preconditioning prkcd prkch puncture ratref reproduced rgs9 rxrg s100a8 sepsis six3 slc17a6 slco1a5 sostdc1 tac1 ttr ulinastatin