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ISYNA1
Description
inositol-3-phosphate synthase 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Molecular Function
Inositol-3-phosphate Synthase Activity
Protein Binding
Isomerase Activity
Biological Process
Inositol Biosynthetic Process
Lipid Metabolic Process
Phospholipid Biosynthetic Process
Pathways
Synthesis of IP2, IP, and Ins in the cytosol
Drugs
2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate
2-Deoxy-Glucitol-6-Phosphate
Glycerin
Diseases
GWAS
Alzheimer's disease (late onset) (
30820047
)
Breast cancer (
23535729
)
Heel bone mineral density (
30598549
)
Novel Interacting Genes
1 novel interacting genes:
GATAD2A
Interacting Genes
6 interacting genes:
DUSP14
GRSF1
OGT
POT1
PPP2CA
TRAF4
Entrez ID
51477
HPRD ID
17163
Ensembl ID
ENSG00000105655
Uniprot IDs
A0A140VK73
Q9NPH2
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Carbohydrate Catabolic Process
Regulation Of ATP Metabolic Process
Regulation Of Glycolytic Process
RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity
RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity
Protein N-acetylglucosaminyltransferase Complex
Negative Regulation Of Non-canonical Inflammasome Complex Assembly
Positive Regulation Of DNA Strand Elongation
Positive Regulation Of Telomeric D-loop Disassembly
G-rich Single-stranded DNA Binding
Regulation Of Purine Nucleotide Metabolic Process
Protein Serine/threonine Phosphatase Activity
Protein Tyrosine Phosphatase Activity
RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity
Positive Regulation Of Telomeric Loop Disassembly
Positive Regulation Of Mitochondrial RNA Catabolic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Generation Of Precursor Metabolites And Energy
Protein O-acetylglucosaminyltransferase Activity
8-hydroxy-2'-deoxyguanosine DNA Binding
Telomeric G-quadruplex DNA Binding
Phosphoprotein Phosphatase Activity
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate
Chromosome
Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress
Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Regulation Of Transcription From RNA Polymerase II Promoter By Glucose
Single-stranded Telomeric DNA Binding
Telomeric D-loop Binding
Telomere Assembly
Non-canonical Inflammasome Complex Assembly
Positive Regulation Of Transcription By Glucose
Shelterin Complex
Mitochondrial RNA Catabolic Process
Regulation Of Primary Metabolic Process
RNA Catabolic Process
Carbon Catabolite Regulation Of Transcription
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Positive Regulation Of Macromolecule Metabolic Process
G-quadruplex RNA Binding
DEAD/H-box RNA Helicase Binding
Protein Serine/threonine Phosphatase Complex
Peptidyl-threonine Dephosphorylation
Regulation Of Transcription By Glucose
Nuclear Telomere Cap Complex
Telomeric D-loop Disassembly
Thioesterase Binding
G-rich Strand Telomeric DNA Binding
Tagcloud
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