LIMA1

Gene Name		LIM domain and actin binding 1
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Cytoplasm Plasma Membrane Focal Adhesion Actin Cytoskeleton Cleavage Furrow
	Molecular Function	Actin Monomer Binding Protein Binding Zinc Ion Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Actin Filament Depolymerization Ruffle Organization Actin Filament Bundle Assembly
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: APP SVIL UBC YWHAG YWHAQ
Entrez ID		51474
HPRD ID		09755
Ensembl ID		ENSG00000050405
Uniprot IDs		Q59FE8 Q9UHB6
PDB IDs		2D8Y
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Cycle Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Positive Regulation Of Cell Cycle Cell Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Death Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Intracellular Transport Regulation Of Cell Cycle Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Mitochondrion Organization Positive Regulation Of Cell Death Establishment Of Localization In Cell G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Kinase Activity Negative Regulation Of Cellular Metabolic Process Notch Signaling Pathway Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Synaptic Growth At Neuromuscular Junction Membrane Organization Negative Regulation Of Protein Metabolic Process Cellular Localization Regulation Of Cell Cycle Collateral Sprouting In Absence Of Injury Intrinsic Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Regulation Of Cell Cycle Phase Transition Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Intracellular Transport Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Axon Choice Point Recognition Positive Regulation Of Signal Transduction
Tagcloud ?		axis cadherin cascade determinants dissemination dnp73 drives emt eplin establish facilitates igf1r insight invade invasion link mechanistic melanoma metastasis metastasize nonmetastatic p73 reduces slug toward unaffected upregulation widely xenografts