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PDCD1
Gene Name
programmed cell death 1
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Molecular Function
Signal Transducer Activity
Protein Binding
Biological Process
Apoptotic Process
Humoral Immune Response
Signal Transduction
Multicellular Organismal Development
T Cell Costimulation
Positive Regulation Of T Cell Apoptotic Process
Pathways
Costimulation by the CD28 family
PD-1 signaling
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
CD274
PDCD1LG2
Entrez ID
5133
HPRD ID
02590
Ensembl ID
ENSG00000188389
Uniprot IDs
Q15116
PDB IDs
2M2D
3RRQ
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Activated T Cell Proliferation
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interferon-gamma Production
Regulation Of Activated T Cell Proliferation
Negative Regulation Of T Cell Proliferation
Negative Regulation Of Lymphocyte Proliferation
Negative Regulation Of Mononuclear Cell Proliferation
T Cell Costimulation
Negative Regulation Of Leukocyte Proliferation
Positive Regulation Of T Cell Proliferation
Regulation Of Interferon-gamma Production
Negative Regulation Of T Cell Activation
Negative Regulation Of Leukocyte Cell-cell Adhesion
Negative Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Lymphocyte Proliferation
Positive Regulation Of Mononuclear Cell Proliferation
Negative Regulation Of Lymphocyte Activation
Negative Regulation Of Cell-cell Adhesion
Regulation Of T Cell Proliferation
Negative Regulation Of Leukocyte Activation
Negative Regulation Of Cell Adhesion
Negative Regulation Of Cytokine Production
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Cell-cell Adhesion
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Negative Regulation Of Immune System Process
Regulation Of Lymphocyte Activation
Regulation Of Cell Activation
Regulation Of Cytokine Production
Regulation Of Cell Adhesion
Negative Regulation Of Cell Proliferation
Positive Regulation Of Interleukin-10 Secretion
Positive Regulation Of Cell Proliferation
Positive Regulation Of Immune System Process
Regulation Of Interleukin-10 Secretion
Positive Regulation Of Interleukin-10 Production
Immune Response
Regulation Of Immune System Process
Toxin Transport
Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production
Regulation Of Cell Proliferation
Positive Regulation Of Cytokine Secretion
Immune System Process
Regulation Of Cytokine Secretion
Positive Regulation Of Protein Secretion
Positive Regulation Of Secretion
Tagcloud
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2c
chordin
chrdl2
desmin
eya2
galectin
granulin
igfs
listed
mef2c
msh
msx1
myocyte
myogenesis
numb
nuprl
pax3
pax7
pbx1
programmed
pseudospiralis
r1
rb1
retinoblastoma
satellite
ski
spiralis
trichinella