CYP39A1

Description		cytochrome P450 family 39 subfamily A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Monooxygenase Activity Iron Ion Binding Protein Binding Steroid 7-alpha-hydroxylase Activity Steroid Hydroxylase Activity Oxysterol 7-alpha-hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Heme Binding 24S-hydroxycholesterol 7-alpha-hydroxylase Activity Metal Ion Binding
	Biological Process	Lipid Metabolic Process Bile Acid Biosynthetic Process Cholesterol Catabolic Process Digestion Steroid Metabolic Process Cholesterol Metabolic Process Sterol Metabolic Process Cholesterol Homeostasis
Pathways		Synthesis of bile acids and bile salts via 24-hydroxycholesterol Endogenous sterols
Drugs
Diseases
GWAS		Normal facial asymmetry (deformation magnitude) ( 30631343)
Interacting Genes		4 interacting genes: GLUL ORM2 SERINC1 SMYD3
Entrez ID		51302
HPRD ID		07067
Ensembl ID		ENSG00000146233
Uniprot IDs		A0A087WTD2 B7Z786 Q9NYL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutamine Synthetase Activity Intracellular Ammonium Homeostasis Glutamine Biosynthetic Process Ammonium Homeostasis L-glutamate Catabolic Process Membrane Biogenesis RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Histone H4 Methyltransferase Activity Histone H3K36 Dimethyltransferase Activity Histone H3K4 Trimethyltransferase Activity Regulation Of Protein Localization To Nucleolus Acetyltransferase Activator Activity
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