PCOLCE

Gene Name		procollagen C-endopeptidase enhancer
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Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Collagen Binding Heparin Binding Peptidase Activator Activity
	Biological Process	Proteolysis Multicellular Organismal Development Positive Regulation Of Peptidase Activity
Pathways		Collagen formation Crosslinking of collagen fibrils Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: COL2A1 COL3A1 ECT2 PLG
Entrez ID		5118
HPRD ID		02603
Ensembl ID		ENSG00000106333
Uniprot IDs		Q15113
PDB IDs		1UAP
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Collagen Fibril Organization Collagen Catabolic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Cardiovascular System Development Cell Morphogenesis Platelet Activation Cell Differentiation Mononuclear Cell Migration Locomotion Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Fibrinolysis Aorta Smooth Muscle Tissue Morphogenesis Movement Of Cell Or Subcellular Component System Development Generation Of Neurons Regulation Of Rho Protein Signal Transduction Neurogenesis Tissue Development Axon Guidance Limb Bud Formation Negative Regulation Of Fibrinolysis Catabolic Process Multicellular Organismal Development Blood Coagulation Anatomical Structure Development Cellular Response To Organic Substance Hemostasis Extracellular Fibril Organization Response To Radiation Activation Of Rac GTPase Activity Regulation Of Fibrinolysis Embryonic Organ Development Muscle Structure Development Blood Vessel Development Heart Development Otic Vesicle Development Axonogenesis Developmental Process Vasculature Development Positive Regulation Of Cdc42 GTPase Activity Skeletal System Development Embryonic Skeletal Joint Morphogenesis Trophoblast Giant Cell Differentiation
Tagcloud ?		apolipoprotein cathepsin cerebrospinal csf dbp dismutase electrophoresis electrospray endopeptidase epilepsy epileptogenesis fam3c igkv1 igl immunoglobulin ionization lambda lobe pathophysiologic proteomic sod1 spots superoxide talin tandem tetranectin tle tn