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SEPSECS

Description Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
Molecular Function
  • TRNA Binding
  • RNA Binding
  • Protein Binding
  • Transferase Activity
  • O-phosphoseryl-tRNA(Sec) Selenium Transferase Activity
Biological Process
  • Selenocysteine Incorporation
  • Conversion Of Seryl-tRNAsec To Selenocys-tRNAsec
  • Translation
Pathways
  • Selenocysteine synthesis
Drugs
  • Pyridoxal phosphate
Diseases
GWAS
  • Tonsillectomy ( 27182965 28928442)
Novel Interacting Genes 2 novel interacting genes: ANAPC4 DNAH1
Interacting Genes 1 interacting genes: DTX2
Entrez ID 51091
HPRD ID 11561
Ensembl ID ENSG00000109618
Uniprot IDs A0A7P0TA23 A1A4F3 Q9HD40
PDB IDs 3HL2 4ZDL 4ZDO 4ZDP 7L1T 7MDL 8G9Z
Enriched GO Terms of Interacting Partners?
  • Inner Dynein Arm
  • Dynein Intermediate Chain Binding
  • Axonemal Dynein Complex Assembly
  • Minus-end-directed Microtubule Motor Activity
  • Inner Dynein Arm Assembly
  • Dynein Light Intermediate Chain Binding
  • Axonemal Dynein Complex
  • Sperm Axoneme Assembly
  • Dynein Complex
  • Protein K11-linked Ubiquitination
  • Anaphase-promoting Complex-dependent Catabolic Process
  • Post-translational Protein Modification
  • Protein Branched Polyubiquitination
  • Protein Ubiquitination
  • Nuclear Periphery
  • Protein Modification By Small Protein Conjugation
  • Anaphase-promoting Complex
  • Epithelial Cilium Movement Involved In Extracellular Fluid Movement
  • Extracellular Transport
  • Axoneme Assembly
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