PCCA

Description		propionyl-CoA carboxylase subunit alpha
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol Catalytic Complex
	Molecular Function	Nucleotide Binding Propionyl-CoA Carboxylase Activity Protein Binding ATP Binding Biotin Binding Ligase Activity Ligase Activity, Forming Carbon-carbon Bonds Enzyme Binding Metal Ion Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Branched-chain Amino Acid Metabolic Process Lipid Catabolic Process Short-chain Fatty Acid Catabolic Process
Pathways		Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Propionyl-CoA catabolism
Drugs		Biotin
Diseases		Propionic acidemia
GWAS		Chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Corpus callosum anterior volume ( 31530798) Metabolite levels ( 23823483) Myopia ( 27182965) Refractive error ( 23396134 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation (ever regular vs never regular) ( 30679032) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		6 interacting genes: ERRFI1 H19 MCC PCCB PJA1 TMEM132D
Entrez ID		5095
HPRD ID		01981
Ensembl ID		ENSG00000175198
Uniprot IDs		P05165
PDB IDs		2CQY 2JKU 7YBU 8XL3 8XL4 8XL5
Enriched GO Terms of Interacting Partners?
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