OSBP

Description		oxysterol binding protein
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Membrane Cell Junction Perinuclear Region Of Cytoplasm Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Oxysterol Binding Lipid Binding Protein Domain Specific Binding Sterol Binding Phosphatidylinositol-4-phosphate Binding Lipid Transfer Activity Sterol Transfer Activity
	Biological Process	Sphingomyelin Biosynthetic Process Bile Acid Biosynthetic Process Lipid Transport Phospholipid Transport Sterol Transport Intracellular Cholesterol Transport Ceramide Transport Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Intermembrane Lipid Transfer Positive Regulation Of Secretory Granule Organization
Pathways		Sphingolipid de novo biosynthesis Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: MARK2
Interacting Genes		4 interacting genes: CSNK2A1 SNAP25 VAPA VAPB
Entrez ID		5007
HPRD ID		01327
Ensembl ID		ENSG00000110048
Uniprot IDs		P22059
PDB IDs		2RR3 7V62
Enriched GO Terms of Interacting Partners?		FFAT Motif Binding COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization By Membrane Tethering Membrane Docking Endoplasmic Reticulum Localization Organelle Localization Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Host-mediated Suppression Of Viral Genome Replication Viral Release From Host Cell Endoplasmic Reticulum Exit Site Vesicle Budding From Membrane Protein-membrane Adaptor Activity Host-mediated Activation Of Viral Process Cadherin Binding Vesicle Organization Organelle Organization Endoplasmic Reticulum Organization Cholesterol Transport Host-mediated Perturbation Of Viral Process Sterol Transport Establishment Of Localization In Cell Host-mediated Perturbation Of Symbiont Process Modulation Of Process Of Another Organism Membrane Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Negative Regulation By Virus Of Viral Protein Levels In Host Cell Viral Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Membrane Fusion Biological Process Involved In Interaction With Host Organic Hydroxy Compound Transport Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape Vesicle Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Presynaptic Dense Core Vesicle Exocytosis Plasma Membrane Protein Folding Positive Regulation Of Aggrephagy Microtubule Bundle Ribbon Synapse Regulation Of Neurofibrillary Tangle Assembly Neuronal Dense Core Vesicle Exocytosis Host-mediated Perturbation Of Viral RNA Genome Replication Microtubule Binding Regulation Of Biological Quality Dense Core Granule Exocytosis Wnt Signaling Pathway
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