EIF2AK4

Gene Name		eukaryotic translation initiation factor 2 alpha kinase 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosolic Ribosome
	Molecular Function	Protein Serine/threonine Kinase Activity Eukaryotic Translation Initiation Factor 2alpha Kinase Activity ATP Binding
	Biological Process	Regulation Of Translational Initiation Protein Phosphorylation Cellular Response To Starvation Negative Regulation Of Translation Endoplasmic Reticulum Unfolded Protein Response Regulation Of Translational Initiation In Response To Stress
Pathways
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Ewing sarcoma ( 22327514)
Protein-protein Interactions		4 interactors: GGNBP1 SMAD1 SMAD4 TGFBR1
Entrez ID		440275
HPRD ID		18447
Ensembl ID		ENSG00000128829
Uniprot IDs		Q9P2K8
PDB IDs
Enriched GO Terms of Interacting Partners?		Endothelial Cell Activation Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of SMAD Protein Import Into Nucleus SMAD Protein Complex Assembly Regulation Of SMAD Protein Import Into Nucleus Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cardiac Epithelial To Mesenchymal Transition Cell Fate Commitment Kidney Development Renal System Development Urogenital System Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cell Morphogenesis Pattern Specification Process Heart Development Cellular Response To Growth Factor Stimulus Neuron Fate Commitment BMP Signaling Pathway Response To Growth Factor Embryonic Pattern Specification Regulation Of Cartilage Development Embryonic Morphogenesis Gamete Generation Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Import Into Nucleus Palate Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Ureteric Bud Development Mesenchymal Cell Development Mesonephric Tubule Development Mesonephric Epithelium Development Sexual Reproduction Mesonephros Development Multicellular Organismal Reproductive Process Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Multicellular Organism Reproduction Regulation Of Cell Development Mesenchymal Cell Differentiation Cardiovascular System Development Mesoderm Development Enzyme Linked Receptor Protein Signaling Pathway Kidney Epithelium Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Tagcloud ?		activates affects arginine coordinately depletion eukaryotic gcn2 hri indirectly inducible innate kinases mediate nitric nos oxide pathological perk phosphorylate physiological pkr synthase uniquely upstream