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MPZ
Gene Name
myelin protein zero
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Myelin Sheath
Molecular Function
Structural Molecule Activity
Biological Process
Synaptic Transmission
Cell-cell Junction Maintenance
Pathways
Drugs
Diseases
GWAS
Visceral adipose tissue adjusted for BMI (
22589738
)
Protein-protein Interactions
3 interactors:
PINX1
PMP22
PSMB3
Entrez ID
4359
HPRD ID
01159
Ensembl ID
ENSG00000158887
Uniprot IDs
P25189
PDB IDs
1N2P
3OAI
Enriched GO Terms of Interacting Partners
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Negative Regulation Of Transferase Activity
Bleb Assembly
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Regulation Of Telomerase Activity
Negative Regulation Of Cell Proliferation
Mitotic Cell Cycle Process
RNA-dependent DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Mitotic Cell Cycle
Negative Regulation Of Catalytic Activity
Mitotic Metaphase Plate Congression
Telomere Maintenance Via Telomere Lengthening
Myelin Assembly
Metaphase Plate Congression
Establishment Of Chromosome Localization
Cell Cycle Process
Cell Death
Death
Regulation Of DNA Biosynthetic Process
Negative Regulation Of DNA Replication
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Cell Cycle
Positive Regulation Of Ligase Activity
Telomere Maintenance
Mitotic Sister Chromatid Segregation
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Sister Chromatid Segregation
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Cell Proliferation
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Negative Regulation Of DNA Metabolic Process
Regulation Of Cell Cycle Arrest
Mitotic DNA Integrity Checkpoint
Tagcloud
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1p35
1q
3q
7p
axonal
charcot
cmt
cmt1b
cmt2
cmt2a
cmt2b
cmt2d
dejerine
demyelinating
genetically
hereditary
hmsn
hypomyelination
inherited
marie
missense
myelin
neuropathies
neuropathy
sardinian
ser44phe
sottas
tooth
zero