LTC4S

Gene Name		leukotriene C4 synthase
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Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Lipid Binding
	Biological Process	Leukotriene Metabolic Process Arachidonic Acid Metabolic Process Leukotriene Biosynthetic Process Lipoxygenase Pathway Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Oxidation-reduction Process Lipoxin Metabolic Process
Pathways		Arachidonic acid metabolism Synthesis of 5-eicosatetraenoic acids Metabolism of lipids and lipoproteins Synthesis of Lipoxins (LX) Synthesis of Leukotrienes (LT) and Eoxins (EX)
Drugs		Glutathione
Diseases
GWAS
Protein-protein Interactions		3 interactors: ALOX5 ALOX5AP MGST1
Entrez ID		4056
HPRD ID		02004
Ensembl ID		ENSG00000213316
Uniprot IDs		Q16873
PDB IDs		2PNO 2UUH 2UUI 3B29 3HKK 3LEO 3PCV
Enriched GO Terms of Interacting Partners?		Lipoxin Metabolic Process Lipoxygenase Pathway Protein Homotrimerization Leukotriene Biosynthetic Process Protein Trimerization Leukotriene Metabolic Process Icosanoid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Arachidonic Acid Metabolic Process Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Cellular Response To Lipid Hydroperoxide Leukotriene Production Involved In Inflammatory Response Protein Homooligomerization Response To Lipid Hydroperoxide Fatty Acid Metabolic Process Protein Oligomerization Small Molecule Metabolic Process Lipid Biosynthetic Process Monocarboxylic Acid Metabolic Process Cellular Response To Hydroperoxide Leydig Cell Differentiation Response To Hydroperoxide Glutathione Derivative Biosynthetic Process Production Of Molecular Mediator Involved In Inflammatory Response Cellular Lipid Metabolic Process Protein Complex Assembly Carboxylic Acid Metabolic Process Cellular Response To Calcium Ion Organic Acid Metabolic Process Lipid Metabolic Process Biosynthetic Process Glutathione Metabolic Process Oxidation-reduction Process Response To Calcium Ion Cellular Response To Metal Ion Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To Inorganic Substance Cellular Component Assembly Response To Xenobiotic Stimulus Peptide Metabolic Process Male Gonad Development Male Sex Differentiation Cellular Response To Oxidative Stress Gonad Development Development Of Primary Sexual Characteristics Cellular Modified Amino Acid Metabolic Process
Tagcloud ?		apcdd1 attributable beadchip clec2d dox doxycycline efnb1 il1rn illumina interrogate ocil ogn opg osteoblast osteoclastogenesis osteoclastogenic paid pluripotent profiled rspo2 runx2 rx2 sema3a sema7a slco2b1 splenocytes st2 tnc tnfrsf11b