LDHB

Name	lactate dehydrogenase B
Structure
Interactors	12 interactors: CEBPA CKS1B CKS2 MYCBP2 OGT PEX5 POT1 PTPRF SDCBP SUMO4 TERF1 USP40
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol Membrane Membrane Raft Extracellular Exosome Oxidoreductase Complex
	Molecular Function	Catalytic Activity Lactate Dehydrogenase Activity L-lactate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Kinase Binding Identical Protein Binding NAD Binding
	Biological Process	Lactate Metabolic Process NAD+ Metabolic Process Carboxylic Acid Metabolic Process Pyruvate Catabolic Process
Pathways	Pyruvate metabolism
Drugs	NADH 4-Hydroxy-1,2,5-oxadiazole-3-carboxylic acid Oxamic Acid Stiripentol Artenimol
GWAS	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223 )
Entrez ID	3945
HPRD ID	01026
Ensembl ID	ENSG00000111716
Uniprot IDs	A0A5F9ZHM4 P07195 Q5U077
PDB IDs	1I0Z 1T2F 7DBJ 7DBK 8QDE
GO Terms Enriched among Interactors ?	Shelterin Complex Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Telomeric Loop Disassembly Telomere Capping G-rich Strand Telomeric DNA Binding Negative Regulation Of Cellular Component Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Nucleobase-containing Compound Metabolic Process Organelle Organization Negative Regulation Of Macromolecule Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Cell Cycle Cyclin-dependent Protein Kinase Holoenzyme Complex Protein Modification Process Regulation Of Cellular Component Organization Chondroitin Sulfate Proteoglycan Binding Interleukin-5 Receptor Complex Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Telomere Maintenance Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding SCF Ubiquitin Ligase Complex Circadian Regulation Of Gene Expression Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Response To Vitamin B2 C/EBP Complex Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Interleukin-5 Receptor Binding Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly