KIF11

Gene Name		kinesin family member 11
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Cytoplasm Spindle Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane
	Molecular Function	Microtubule Motor Activity ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Protein Kinase Binding Protein Complex Binding
	Biological Process	Microtubule-based Movement Spindle Organization Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Division Mitotic Centrosome Separation Blood Coagulation Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Mitotic Centrosome Separation Cell Division Mitotic Spindle Assembly
Pathways		MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs		Adenosine-5\'-Diphosphate 3-[(5s)-1-Acetyl-3-(2-Chlorophenyl)-4,5-Dihydro-1h-Pyrazol-5-Yl]Phenol Monastrol (4R)-4-(3-HYDROXYPHENYL)-N,N,7,8-TETRAMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE (5R)-N,N-DIETHYL-5-METHYL-2-[(THIOPHEN-2-YLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE (2S)-4-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide [(4R)-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL](PHENYL)METHANONE (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE (2S)-4-(2,5-DIFLUOROPHENYL)-N,N-DIMETHYL-2-PHENYL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE (5S)-5-(3-AMINOPROPYL)-3-(2,5-DIFLUOROPHENYL)-N-ETHYL-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE
Diseases
GWAS		Type 2 diabetes ( 21490949)
Protein-protein Interactions		4 interactors: AURKA CDK1 DCTN1 PPARG
Entrez ID		3832
HPRD ID		01023
Ensembl ID		ENSG00000138160
Uniprot IDs		P52732
PDB IDs		1II6 1Q0B 1X88 1YRS 2FKY 2FL2 2FL6 2FME 2G1Q 2GM1 2IEH 2PG2 2Q2Y 2Q2Z 2UYI 2UYM 2WOG 2X2R 2X7C 2X7D 2X7E 2XAE 3CJO 3HQD 3K3B 3K5E 3KEN 3L9H 3ZCW 4A1Z 4A28 4A50 4A51 4A5Y 4AP0 4AQV 4AQW 4AS7 4B7B 4BBG 4BXN
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Mitotic Nuclear Division Histone Phosphorylation Centrosome Cycle Regulation Of Cellular Protein Metabolic Process Organ Regeneration Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Glial Cell Differentiation Regulation Of Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Nervous System Development Centrosome Organization Regulation Of Gliogenesis Microtubule Organizing Center Organization Mitotic Cell Cycle Microtubule-based Process Peptidyl-serine Phosphorylation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of DNA Replication Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Response To Diuretic Negative Regulation Of Spindle Checkpoint Pronuclear Fusion Regulation Of Cell Development Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Cholesterol Transporter Activity Spindle Assembly Involved In Female Meiosis I Cellular Response To Vitamin E Cell Cycle Process Positive Regulation Of Metabolic Process Spindle Assembly Involved In Meiosis Cellular Response To Insulin Stimulus Positive Regulation Of Protein Catabolic Process Spindle Stabilization Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cell Cycle Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of Cell Cycle
Tagcloud ?		affymetrix annotations apdf aurka bicarbonate blpdf bpdf buffered ccnb1 ccne2 cdk1 containingpdf cpdf diamond diluted genechip icodextrin insufficiently ipdf kif14 lpdf mesothelial omentum pdf pmc repressors smc4 u133plus2 uremic