JARID2

Description		jumonji and AT-rich interaction domain containing 2
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion Histone Methyltransferase Complex ESC/E(Z) Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Histone Demethylase Activity Ubiquitin Binding Histone H3K27 Methyltransferase Activity Ubiquitin-modified Histone Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Liver Development Chromatin Organization Chromatin Remodeling Central Nervous System Development Cell Population Proliferation Regulation Of Gene Expression Cell Differentiation Regulation Of Cell Population Proliferation Negative Regulation Of DNA-templated Transcription Spleen Development Thymus Development System Development Stem Cell Differentiation Cardiac Muscle Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Proliferation Random Inactivation Of X Chromosome Facultative Heterochromatin Formation Protein Localization To Pericentric Heterochromatin Cellular Response To Leukemia Inhibitory Factor
Pathways		PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 31043758) Chronotype ( 30696823) Hand grip strength ( 29691431) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 32888494) Lymphoma ( 23349640) Multiple myeloma ( 27363682) Multiple sclerosis (severity) ( 19010793) Nevus count or cutaneous melanoma ( 32341527) Ovarian reserve ( 22116950)
Interacting Genes		3 interacting genes: GATA4 NKX2-5 SETDB1
Entrez ID		3720
HPRD ID		03355
Ensembl ID		ENSG00000008083
Uniprot IDs		Q92833
PDB IDs		4X3E 5HYN 5LS6 5WAI 6C23 6C24 6NQ3 6WKR 7KSO 8TB9 8VMI 8VML 8VNV 8VNZ 9C8U 9DCH
Enriched GO Terms of Interacting Partners?		Atrioventricular Node Development Atrial Septum Morphogenesis Aortic Valve Morphogenesis Cardiac Muscle Cell Differentiation Negative Regulation Of Striated Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Cardiac Ventricle Morphogenesis DNA-binding Transcription Activator Activity Cardiac Septum Development Cardiocyte Differentiation Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Muscle Cell Apoptotic Process Heart Valve Morphogenesis Mesenchyme Development Cardiac Muscle Tissue Development Heart Looping Embryonic Heart Tube Morphogenesis Striated Muscle Cell Differentiation Cardiac Septum Morphogenesis Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Muscle Cell Differentiation Epithelial Tube Morphogenesis Striated Muscle Tissue Development Septum Secundum Development Nkx-2.5 Complex Purkinje Myocyte Differentiation RNA Polymerase II Transcription Regulator Complex Muscle Tissue Development Regulation Of Muscle Contraction Atrial Cardiac Muscle Cell Development Atrioventricular Node Cell Fate Commitment Cell Fate Commitment Atrial Septum Secundum Morphogenesis RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Heart Contraction His-Purkinje System Cell Differentiation Pulmonary Myocardium Development Proepicardium Development Ventricular Cardiac Myofibril Assembly Right Ventricular Cardiac Muscle Tissue Morphogenesis Embryonic Heart Tube Anterior/posterior Pattern Specification Regulation Of Blood Circulation Positive Regulation Of Cardioblast Differentiation Atrioventricular Node Cell Development Bundle Of His Development Transcription Cis-regulatory Region Binding Regulation Of Muscle System Process Cardiac Muscle Tissue Regeneration Histone H3K9 Trimethyltransferase Activity
Tagcloud ?