JARID2

Gene Name		jumonji, AT rich interactive domain 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex ESC/E(Z) Complex
	Molecular Function	DNA Binding Chromatin Binding Histone Demethylase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Liver Development Transcription, DNA-templated Central Nervous System Development Negative Regulation Of Cell Proliferation Gene Expression Chromatin Modification Negative Regulation Of Histone Methylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Spleen Development Thymus Development Stem Cell Differentiation Positive Regulation Of Histone H3-K9 Methylation
Pathways		Epigenetic regulation of gene expression PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Lymphoma ( 23349640) Multiple sclerosis (severity) ( 19010793) Ovarian reserve ( 22116950)
Protein-protein Interactions		3 interactors: GATA4 NKX2-5 SETDB1
Entrez ID		3720
HPRD ID		03355
Ensembl ID		ENSG00000008083
Uniprot IDs		F5H590 Q92833
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cardioblast Differentiation Septum Secundum Development Atrial Septum Morphogenesis Cardiac Right Ventricle Morphogenesis Atrial Septum Development Cardiac Atrium Morphogenesis Cardiac Muscle Tissue Growth Regulation Of Cardiac Muscle Cell Proliferation Growth Positive Regulation Of Stem Cell Differentiation Ventricular Cardiac Muscle Tissue Development Ventricular Septum Development Cardiac Septum Morphogenesis Regulation Of Heart Growth Regulation Of Cardiac Muscle Tissue Development Heart Looping Determination Of Heart Left/right Asymmetry Embryonic Heart Tube Morphogenesis Cardiac Muscle Cell Development Cardiac Ventricle Morphogenesis Regulation Of Cardiac Muscle Contraction BMP Signaling Pathway Cardiac Septum Development Embryonic Heart Tube Development Regulation Of Striated Muscle Contraction Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Canonical Wnt Signaling Pathway Organ Growth Regulation Of Organ Growth Cardiac Ventricle Development Determination Of Left/right Symmetry Cardiac Muscle Cell Differentiation Determination Of Bilateral Symmetry Cardiocyte Differentiation Regulation Of Striated Muscle Tissue Development Cardiac Chamber Development Embryo Development Purkinje Myocyte Differentiation Atrioventricular Node Cell Fate Commitment Lung Lobe Formation Regulation Of Muscle Contraction Striated Muscle Cell Development Regulation Of Heart Contraction Muscle Cell Development Cardiac Muscle Tissue Development Mesenchyme Development Right Ventricular Cardiac Muscle Tissue Morphogenesis Atrioventricular Node Cell Development Heart Morphogenesis
Tagcloud ?		a549 antagonized catalyzes cdh1 colon conversion crucial discovered emt ezh2 h3k27 ht29 immunoprecipitation interacting knockdown mesenchymal methylation microrna morphological occupancies polycomb prc2 repression repressive ss tgf transforming transition zeb