ITIH4

Gene Name		inter-alpha-trypsin inhibitor heavy chain family, member 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Acute-phase Response Negative Regulation Of Endopeptidase Activity Hyaluronan Metabolic Process Response To Cytokine
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Immune reponse to smallpox (secreted IL-2) ( 22610502) Schizophrenia ( 21926974) Ulcerative colitis ( 23128233)
Protein-protein Interactions		3 interactors: DNAJC1 GRB2 TP63
Entrez ID		3700
HPRD ID		02781
Ensembl ID		ENSG00000055955
Uniprot IDs		B2RMS9 B7ZKJ8 Q14624
PDB IDs
Enriched GO Terms of Interacting Partners?		Signal Transduction In Response To DNA Damage Cellular Response To Radiation Response To Ionizing Radiation Ectoderm And Mesoderm Interaction Epidermal Cell Division Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Regulation Of Epidermal Cell Division Female Genitalia Morphogenesis Aging Cloacal Septation Urinary Bladder Development Positive Regulation Of Fibroblast Apoptotic Process Cloaca Development Prostatic Bud Formation Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of Mesoderm Development Positive Regulation Of Keratinocyte Proliferation Polarized Epithelial Cell Differentiation Protein Oligomerization Response To Radiation Replicative Cell Aging Negative Regulation Of Cellular Senescence Lateral Sprouting From An Epithelium Negative Regulation Of Epidermal Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Reproductive Structure Development Reproductive System Development Morphogenesis Of An Epithelium DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cell Aging Regulation Of Body Fluid Levels Keratinocyte Proliferation Establishment Of Skin Barrier Establishment Of Planar Polarity Embryonic Morphogenesis Tissue Morphogenesis Epithelial Cell Differentiation Involved In Prostate Gland Development Regulation Of Proteolysis Genitalia Morphogenesis Regulation Of Water Loss Via Skin Post-anal Tail Morphogenesis Regulation Of Fibroblast Apoptotic Process Developmental Process Involved In Reproduction Regulation Of Keratinocyte Proliferation Labyrinthine Layer Morphogenesis Female Genitalia Development Sympathetic Nervous System Development
Tagcloud ?		arranged borders ccaat consists cotransfection direction dnase duplication ebp ebpalpha ebpbeta exon exons footprinting h1 heavy hepg2 intron inversion itih1 itih3 kilobase opposite pair rounds shares transcribed trypsin