IMPDH1

Gene Name		IMP (inosine 5-monophosphate) dehydrogenase 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cell Junction
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Metal Ion Binding
	Biological Process	Purine Nucleobase Metabolic Process GMP Biosynthetic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Small Molecule Metabolic Process Lymphocyte Proliferation Nucleobase-containing Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Purine ribonucleoside monophosphate biosynthesis Purine metabolism Metabolism of nucleotides
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid 6-Chloropurine Riboside, 5\'-Monophosphate
Diseases
GWAS
Protein-protein Interactions		2 interactors: GMNN HTRA1
Entrez ID		3614
HPRD ID		08853
Ensembl ID		ENSG00000106348
Uniprot IDs		B3KRZ3 E7EQS0 P20839
PDB IDs		1JCN
Enriched GO Terms of Interacting Partners?		Dentinogenesis Organ Morphogenesis Negative Regulation Of Defense Response To Virus Negative Regulation Of BMP Signaling Pathway Negative Regulation Of DNA Replication Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Defense Response To Virus Regulation Of BMP Signaling Pathway Negative Regulation Of DNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Odontogenesis Of Dentin-containing Tooth Regulation Of DNA Replication Anatomical Structure Morphogenesis Odontogenesis
Tagcloud ?		abcc4 abcc5 all97 atp6ap2 caucasian childhood cytotoxicity frmd4b genotyped gng2 itpa kcnma1 lymphoblastic lymphoblastoid mercaptopurine nme1 outside shifts slc28a3 snp snps tagsnps thioguanine thiopurine thiopurines top uk validation xdh