IL5

Gene Name		interleukin 5
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Interleukin-5 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Positive Regulation Of B Cell Proliferation Positive Regulation Of Eosinophil Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of JAK-STAT Cascade Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Immunoglobulin Secretion Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Podosome Assembly
Pathways		Signaling by GPCR G-protein beta:gamma signalling Cytokine Signaling in Immune system GPCR downstream signaling Signaling by Interleukins Interleukin receptor SHC signaling G beta:gamma signalling through PI3Kgamma Interleukin receptor SHC signaling GPVI-mediated activation cascade Interleukin-2 signaling Platelet activation, signaling and aggregation Interleukin-3, 5 and GM-CSF signaling
Drugs		Pranlukast
Diseases
GWAS		Eosinophil counts ( 19198610) Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		1 interactors: IL5RA
Entrez ID		3567
HPRD ID		00997
Ensembl ID		ENSG00000113525
Uniprot IDs		P05113
PDB IDs		1HUL 3QT2 3VA2
Enriched GO Terms of Interacting Partners?		Interleukin-5-mediated Signaling Pathway Regulation Of Interleukin-5 Production Inflammatory Response To Antigenic Stimulus
Tagcloud ?		1e6 adhesion airway airways bal bronchial bronchoalveolar eosinophil eosinophilia eosinophils epo examines fluid guinea hp1 hyperresponsiveness infiltration intraairway intranasally isotype lavage mab peroxidase pig reactivity seems vasculature vehicle vla