IFNB1

Gene Name		interferon, beta 1, fibroblast
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Type I Interferon Receptor Binding
	Biological Process	Adaptive Immune Response T Cell Activation Involved In Immune Response B Cell Activation Involved In Immune Response Natural Killer Cell Activation Involved In Immune Response Humoral Immune Response Cell Surface Receptor Signaling Pathway Blood Coagulation Response To Virus Cytokine-mediated Signaling Pathway Natural Killer Cell Activation B Cell Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Cellular Response To Interferon-beta B Cell Proliferation Defense Response To Bacterium Response To Exogenous DsRNA Negative Regulation Of Viral Genome Replication Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of T Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway Cellular Response To Exogenous DsRNA Negative Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Regulation of IFNA signaling Cellular Senescence Interferon Signaling Cytokine Signaling in Immune system Factors involved in megakaryocyte development and platelet production TRAF3-dependent IRF activation pathway RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Oxidative Stress Induced Senescence TRAF6 mediated IRF7 activation Interferon alpha/beta signaling Innate Immune System
Drugs		Beta-D-Glucose Alpha-D-Mannose
Diseases
GWAS
Protein-protein Interactions		2 interactors: IFNAR1 IFNAR2
Entrez ID		3456
HPRD ID		00972
Ensembl ID		ENSG00000171855
Uniprot IDs		P01574 Q5VWC9
PDB IDs		1AU1
Enriched GO Terms of Interacting Partners?		Regulation Of Type I Interferon-mediated Signaling Pathway JAK-STAT Cascade Regulation Of Cytokine-mediated Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Regulation Of Innate Immune Response Response To Virus Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Type I Interferon Biosynthetic Process Response To Cytokine Response To Other Organism Response To Biotic Stimulus Innate Immune Response Type I Interferon Production Response To Interferon-alpha Regulation Of Immune Response Positive Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Interleukin-1 Secretion Regulation Of Interleukin-1 Beta Secretion Cytokine Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Production Cytokine Metabolic Process Positive Regulation Of Interleukin-1 Production Immune Response Regulation Of Immune System Process Defense Response Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interferon-gamma Production Response To External Stimulus Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Interferon-gamma Production Positive Regulation Of Cytokine Secretion Immune System Process Regulation Of Cytokine Secretion Response To Organic Substance Cytokine Production Defense Response To Virus Regulation Of Signal Transduction Positive Regulation Of Protein Secretion Regulation Of Signaling Cell Surface Receptor Signaling Pathway Response To Stress T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion
Tagcloud ?		acting activates adaptor cgamp constitutively cytosol dimerization downstream effectively failed hsv ifns innate irf3 lethality mediates mediating messenger mita neurotropic screen sensing sensor sting tbk1 titers triggered viruses zdhhc1