NDST1

Name	N-deacetylase and N-sulfotransferase 1
Structure
Novel Interactors	7 novel interactors: ABLIM3 ADAM18 CAMK2A HMGXB3 ITGA11 ST6GALNAC1 SYNPO
Interactors	2 interactors: LCOR RUNX1
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Trans-Golgi Network Membrane
	Molecular Function	Catalytic Activity Protein Binding Sulfotransferase Activity Heparan Sulfate N-sulfotransferase Activity Transferase Activity Hydrolase Activity Deacetylase Activity N-acetylglucosamine Deacetylase Activity Heparan Sulfate N-deacetylase Activity
	Biological Process	Polysaccharide Biosynthetic Process Cardiac Septum Development Inflammatory Response Heart Development Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Animal Organ Morphogenesis Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Heparin Proteoglycan Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development
Pathways	HS-GAG biosynthesis
Drugs	Adenosine 3',5'-diphosphate
GWAS	Appendicular lean mass ( 33097823 ) Blood protein levels ( 30072576 ) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025 ) Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 ) Neutrophil count ( 32888494 )
Entrez ID	3340
HPRD ID	02912
Ensembl ID	ENSG00000070614
Uniprot IDs	A8K8T3 P52848
PDB IDs	1NST 8CCY 8CD0 8CHS