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HSD17B4
Gene Name
hydroxysteroid (17-beta) dehydrogenase 4
Image
Gene Ontology Annotations
Cellular Component
Mitochondrion
Peroxisome
Peroxisomal Membrane
Peroxisomal Matrix
Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
3-hydroxyacyl-CoA Dehydrogenase Activity
Receptor Binding
Long-chain-enoyl-CoA Hydratase Activity
Isomerase Activity
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA Hydratase Activity
Protein Homodimerization Activity
17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity
Biological Process
Very Long-chain Fatty Acid Metabolic Process
Osteoblast Differentiation
Fatty Acid Beta-oxidation
Bile Acid Biosynthetic Process
Metabolic Process
Bile Acid Metabolic Process
Androgen Metabolic Process
Estrogen Metabolic Process
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Unsaturated Fatty Acid Metabolic Process
Alpha-linolenic Acid Metabolic Process
Very Long-chain Fatty-acyl-CoA Metabolic Process
Medium-chain Fatty-acyl-CoA Metabolic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Oxidation-reduction Process
Sertoli Cell Development
Pathways
Beta-oxidation of pristanoyl-CoA
Bile acid and bile salt metabolism
alpha-linolenic acid (ALA) metabolism
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Metabolism of lipids and lipoproteins
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Synthesis of bile acids and bile salts
Beta-oxidation of very long chain fatty acids
Peroxisomal lipid metabolism
Drugs
NADH
Nicotinamide-Adenine-Dinucleotide
3r-Hydroxydecanoyl-Coa
Diseases
GWAS
Protein-protein Interactions
7 interactors:
ACTB
BAK1
CASP9
CDK7
MAPK8
NDRG1
SNCA
Entrez ID
3295
HPRD ID
03514
Ensembl ID
ENSG00000133835
Uniprot IDs
B2R659
E7ET17
E7EWE5
G5E9S2
P51659
PDB IDs
1IKT
1S9C
1ZBQ
Enriched GO Terms of Interacting Partners
?
Response To Inorganic Substance
Cellular Response To Stress
Response To Metal Ion
Response To Stress
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Immune System Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Positive Regulation Of Endopeptidase Activity
Response To UV
Positive Regulation Of Peptidase Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cell Activation
Regulation Of Cysteine-type Endopeptidase Activity
Response To Other Organism
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Response To Biotic Stimulus
Positive Regulation Of Intracellular Transport
Protein Processing
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Innate Immune Response
Signaling
Fc Receptor Signaling Pathway
Response To External Stimulus
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Calcium Ion Transport Into Cytosol
Cell Communication
Membrane Organization
Positive Regulation Of Proteolysis
Regulation Of Cellular Protein Metabolic Process
Response To Lipopolysaccharide
Aging
Apoptotic Process
Response To Molecule Of Bacterial Origin
Response To Light Stimulus
Programmed Cell Death
Apoptotic Signaling Pathway
Positive Regulation Of Hydrolase Activity
Cell Death
Regulation Of Protein Metabolic Process
Death
Positive Regulation Of Mitochondrion Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Tagcloud
?
aas
aass
abused
anabolic
androgenic
arr19
cyp11a1
cyp17a1
dax1
disturbed
enanthate
gnrhr
hsd3b1
hsd3b5
insl3
intramuscular
leydig
lhcgr
milieu
oppositely
prka
prlr1
prlr2
prolactin
star
steroidogenesis
steroidogenic
testosterone
tspo